ANESTHESIA AND ANALGESIA麻醉与镇痛
ANESTHESIA AND ANALGESIA(英文缩写 ANESTH ANALG),ISSN 0003-2999,eISSN 1526-7598,中文译名:麻醉与镇痛 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 6.627 | Q1 |
| 2022 | 5.700 | Q1 |
| 2023 | 4.600 | Q1 |
| 2024 | 3.800 | Q1 |
| 2025 | 4.700 | Q1 |
ANESTHESIA AND ANALGESIA 最新收录文献
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1. Conventional Prothrombin Time and Activated Partial Thromboplastin Time Mask Citrate-Induced Divalent Cation Depletion During Frozen Plasma Transfusion.
1. 常规凝血酶原时间和活化部分凝血活酶时间掩盖了冰冻血浆输注过程中柠檬酸盐诱导的二价阳离子耗竭PMID:日期:2026-09-30该文献暂无摘要。
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2. Effect of Autonomic Nervous System Dysfunction in Breast Cancer Patients on Post-induction and Early Intraoperative Hypotension: A Prospective Observational Study.
2. 乳腺癌患者自主神经系统功能障碍对诱导后及术早期低血压的影响：一项前瞻性观察性研究PMID:日期:2026-09-24Autonomic nervous system (ANS) dysfunction is increasingly recognized as a significant complication in cancer patients, potentially affecting perioperative hemodynamic stability. We evaluated the prevalence of ANS dysfunction in breast cancer patients and its association with post-induction hypotension during surgery. This prospective, observational, double-blinded study was conducted from September 2018 to August 2019 at the All India Institute of Medical Sciences (AIIMS), New Delhi. Sixty-nine adult female patients with breast cancer scheduled for surgery under general anesthesia were enrolled. Preoperative autonomic function was assessed using standardized cardiovascular tests, including heart rate response to deep breathing, Valsalva maneuver, handgrip test, cold pressor test, and postural challenge test. ANS dysfunction was defined as abnormal results in two or more tests. Post-induction hypotension was defined as >30% decrease from baseline systolic blood pressure or absolute SBP <90 mm Hg. Among 62 patients with complete autonomic test results, ANS dysfunction was highly prevalent (49/62, 79.0%). Sympathetic dysfunction was present in 38 of 62 (61.3%), parasympathetic dysfunction in 25 of 62 (40.3%), and combined dysfunction in 14 of 62 (22.6%) of patients. The overall incidence of post-induction hypotension was 22 of 69 (32%). However, no significant association was found between ANS dysfunction and post-induction hypotension (sympathetic: odds ratio [OR], 1.04; 95% confidence interval [CI], 0.35-3.07; P = 1.00 and parasympathetic: OR, 1.17; 95% CI, 0.40-3.41; P = .79 and combined: OR, 1.11; 95% CI, 0.32-3.87; P = 1.00). Age was significantly associated with parasympathetic dysfunction (mean ± standard deviation [SD], 52.3 ± 9.7 vs 42.8 ± 9.9 years; P < .001), whereas comorbidities were not significantly associated (8/25 [32.0%] vs 4/37 [10.8%]; P = .052). Despite a high prevalence of ANS dysfunction in breast cancer patients, it was not associated with post-induction hypotension. The occurrence of hypotension appears independent of autonomic status in this population, suggesting that other mechanisms may contribute to perioperative hemodynamic instability.
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3. Hospital Economic Burden of Pediatric Day-of-Surgery Cancellations in US Children's Hospitals: National Projections.
3. 美国儿童医院小儿手术当日取消的医院经济负担：全国预测PMID:日期:2026-09-24该文献暂无摘要。
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5. Batching, Mass Scale, and Lean Principles: Optimizing Perioperative Services.
PMID:日期:2026-09-23该文献暂无摘要。
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7. Global Clinical Research in Anesthesiology, 2005-2025: A Bibliometric Extension.
PMID:日期:2026-09-23该文献暂无摘要。
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8. Evaluating the Impact of Leukotriene Receptor Antagonists on Postoperative Acute Kidney Injury: A Retrospective Study.
PMID:日期:2026-09-23Postoperative acute kidney injury (AKI) is a major complication after oncological surgery, associated with increased morbidity and mortality. Experimental and clinical evidence suggests that leukotriene receptor antagonists, such as montelukast, may reduce inflammation and oxidative stress, potentially protecting against renal injury. In the current study, we investigated the association of perioperative use of leukotriene receptor antagonists and postoperative AKI. Specifically, we hypothesized that leukotriene receptor antagonists, such as montelukast and zafirlukast, would be associated with a lower postoperative incidence of AKI. This single-center retrospective study included adult patients undergoing oncological surgery between April 1, 2016, and September 30, 2025. The primary endpoint was AKI within 7 days of surgery, defined by Kidney Disease Improving Global Outcomes (KDIGO). Secondary endpoints were 30-day postoperative complications, length of hospital stay, and hospital stay costs. A propensity score-overlap weighting (OW) was applied to balance potential confounders identified through univariate analysis and biological plausibility. After balancing, a Poisson regression model with robust standard errors was used to assess associations with outcomes. Of the total 45,751 participants, 555 (1.2%) received a leukotriene receptor antagonist. After weighting for overlap, exposure to the leukotriene receptor antagonist was not significantly associated with AKI 7 days after surgery (risk ratio [RR], 0.79; 95% confidence interval [CI], 0.60-1.06; P = .12). The duration of post-anesthesia care unit (PACU) admission was slightly shorter in leucotriene antagonist users (adjusted mean difference of -5.84 minutes; 95% CI, -14.46 to 2.78; P = .184). A statistically significantly longer hospitalization was observed among leukotriene antagonist users, with a mean adjusted difference of 1.55 days (95% CI, 0.86-2.24; P < .001). The use of leukotriene receptor antagonists was also associated with a higher adjusted risk of surgical reintervention at 7 days: 38.37% vs 33.92%, with an adjusted risk difference of 4.45% (95% CI, 0.31-8.59; P = .035). The adjusted readmission risk at 7 days was 3.52% vs 2.02%, with an adjusted risk difference of 1.49% (95% CI, -0.07 to 3.05; P = .061). The adjusted risks of intensive care unit (ICU) admission were 2.96% vs 2.63%, with an adjusted risk difference of 0.32% (95% CI, -1.11 to 1.76; P = .658). Perioperative use of leukotriene receptor antagonists was not significantly associated with a lower risk of postoperative AKI following oncologic surgery. Further prospective and mechanistic studies are needed to clarify whether leukotriene receptor antagonists exert renoprotective effects in surgical patients.
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9. Intraoperative Ketamine and Chronic Opioid Use After Lumbar Spine Surgery in Patients With and Without Opioid-Use Disorder: A Retrospective Database Analysis.
9. 腰椎手术中术中氯胺酮与慢性阿片类药物使用：对有和无阿片使用障碍患者的回顾性数据库分析PMID:日期:2026-09-23Persistent opioid use after lumbar spine surgery (LSS) remains a major clinical concern. Ketamine is frequently included in multimodal perioperative analgesic regimens for its attenuating effects on central sensitization and its potential to reduce acute postoperative pain and opioid requirements. However, evidence regarding whether intraoperative ketamine influences longer-term outpatient postoperative opioid use is limited and mixed. We aimed to evaluate whether intraoperative ketamine administration is associated with differences in chronic postoperative opioid use after LSS, stratified by preoperative opioid exposure status. We performed a propensity-matched retrospective cohort study using the U.S. based TriNetX Global Research Network-a database containing de-identified electronic health records-including adult patients who underwent LSS between January 2010 and December 2024. Patients were grouped based on receipt of an intraoperative ketamine and stratified by preoperative opioid status (opioid-naive or with opioid-use disorder [OUD]). Propensity score matching was used to balance demographic characteristics and relevant comorbidities. The primary outcome was the presence of outpatient opioid prescriptions at 48 hours, 6 weeks, 3, 6, and 12 months after surgery. Secondary outcomes included opioid-related adverse events and new diagnosis of OUD within 12 months of surgery. After matching, 53,639 opioid-naive patients and 2031 patients with OUD were analyzed. In opioid-naive patients, intraoperative ketamine exposure was associated with higher rates of outpatient opioid prescribing in the early postoperative period at 48 hours (P < .001; risk ratio [RR] 1.23; 95% confidence interval [CI], 1.22-1.25) and 6 weeks (P < .001; RR 1.14; 95% CI, 1.10-1.18), whereas no meaningful differences were observed at 3, 6, or 12 months. In patients with OUD, ketamine exposure was associated with higher rates of opioid prescribing only through 48 hours postoperatively. Opioid-related adverse events and new OUD diagnoses were not reduced but were, in fact, similar or more frequent among ketamine-exposed patients. In this large, real-world cohort, intraoperative ketamine was not associated with lower rates of chronic opioid dispensing after LSS in either opioid-naive or patients with OUD. These database findings reflect the absence of a detectable population-level opioid-sparing signal, and do not exclude dose- or protocol-dependent effects.
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10. Defining a Shortfall in the Anesthesiologist Workforce by Geography in the United States: Projections to 2037.
PMID:日期:2026-09-23There is a paucity of contemporary research on the supply and demand of the anesthesiologist workforce in the United States. This study analyzed US federal government projections on the supply and demand of the anesthesiologist and certified registered nurse anesthetist (CRNA) workforces across the US. This was a microsimulation of anesthesiologists and CRNAs in the United States using data from the Health Workforce Simulation Model. Supply was synonymous with the number of full-time equivalent (FTE) personnel at a given time point, while demand was defined as the projected number of FTE personnel needed. Workforce adequacy was defined as the ratio of supply over demand. A shortfall was determined when demand exceeded supply and surplus was determined when supply exceeded demand. From 2025 to 2037, the number of anesthesiologists was projected to decline from 53,840 to 52,310 FTEs (-2.8%). Over the same period, demand was projected to increase from 56,680 to 60,760 FTEs (+7.2%). As a result, the anesthesiologist shortfall was projected to worsen from supply meeting 95.0% of demand to 86.1%. In contrast, the number of CRNAs was projected to increase from 62,180 to 74,680 FTEs (+20.1%) while demand was projected to increase from 60,890 to 65,300 FTEs (+7.2%). Accordingly, the CRNA workforce was projected to have a surplus of 14.4% by 2037. In 2037, nonmetropolitan areas were projected to have greater anesthesiologist workforce shortfalls (supply meeting 52.7% demand) than metropolitan areas (supply meeting 84.1% demand). By 2037, the South was projected to have the greatest anesthesiologist workforce shortfall (supply meeting 71.1% demand) while the Northeast was projected to have a surplus (107%). In 2037, the states with the greatest anesthesiologist workforce shortfalls were projected to be Idaho (supply meeting 27.5% demand), New Mexico (47.2%), and Rhode Island (52.4%). By 2037, anesthesiology was projected to rank eight of 20 specialties for largest physician workforce shortfall. National workforce shortages are anticipated for anesthesiologists and are greatest in nonmetropolitan areas, the South, and certain states. Future strategies are needed to increase the supply of anesthesiologists in areas with identified deficiencies.