乳酸菌作为益生菌缓解牛疾病机制的最新研究：综述
The current studies on the mechanisms of lactic acid bacteria as probiotics in the alleviate of bovine diseases: a review.
摘要(中文译文)
乳酸菌（LAB）是一种有望替代抗生素用于治疗典型牛病的益生菌选择，包括但不限于乳腺炎、炎症性肠病、腹泻和子宫内膜炎。本综述系统讨论了乳酸菌的治疗机制，包括竞争性排斥病原体、合成有机酸、细菌素和短链脂肪酸等抗菌产物、通过调节紧密连接恢复黏膜屏障完整性，以及抑制NF-κB和MAPK等促炎通路以调节宿主免疫反应。所有这些机制均可减轻炎症、改善肠道和乳腺状况并提高生产水平。乳酸菌是减少抗生素使用和抗生素耐药性的有效且长期的解决方案。本综述将为将乳酸菌引入兽医实践奠定理论基础，并促进可持续畜牧业发展。
Abstract
Lactic acid bacteria (LAB) are an encouraging probiotic option to antibiotics in treating typical bovine diseases, including but not limited to, mastitis, inflammatory bowel disease, diarrhea, and endometritis. The review discusses the therapeutic mechanisms of LAB in a systematic manner including competitive exclusion of pathogens, synthesis of antimicrobial products such as organic acids, bacteriocins, and short-chain fatty acids, recovery of mucosal barrier integrity by regulating tight junctions, and suppression of pro-inflammatory pathways, such as NF-κB and MAPK, to modulate the host immune response. All these mechanisms lower the inflammation, improve the condition of the gut and mammary glands and increase the level of productivity. LAB are an effective and long-term solution to decrease the consumption of antibiotics and antibiotic resistance. This review will form a theoretical basis of introducing LAB into veterinary practice and promote sustainable animal husbandry.
如何引用
AMA
Chun-Ling Guo, Lin-Yue Zhou, Shun-Yi Ji, Han-Jia Zhang, Zhi-Rui Ren, Xiao Tang, et al. The current studies on the mechanisms of lactic acid bacteria as probiotics in the alleviate of bovine diseases: a review.. Frontiers in cellular and infection microbiology. 2026; doi:10.3389/fcimb.2026.1899278.
APA
Chun-Ling Guo, Lin-Yue Zhou, Shun-Yi Ji, Han-Jia Zhang, Zhi-Rui Ren, Xiao Tang, et al (2026). The current studies on the mechanisms of lactic acid bacteria as probiotics in the alleviate of bovine diseases: a review.. Frontiers in cellular and infection microbiology. https://doi.org/10.3389/fcimb.2026.1899278
GB/T 7714
Chun-Ling Guo, Lin-Yue Zhou, Shun-Yi Ji, Han-Jia Zhang, Zhi-Rui Ren, Xiao Tang, et al. The current studies on the mechanisms of lactic acid bacteria as probiotics in the alleviate of bovine diseases: a review.[J]. Frontiers in cellular and infection microbiology, 2026 doi:10.3389/fcimb.2026.1899278.
在 PubMed增强版 阅读全文
翻译全文 · AI 文献问答 · PDF 原文下载 · 引用导出