卒中患者IQCODE简明版
IQCODE-Brief Version in Stroke Patients.
摘要(中文译文)
卒中后认知障碍在卒中后十分常见。本研究旨在采用基于知情者的认知障碍筛查方法，检验IQCODE简版在卒中患者中的心理测量学特性、因子结构及筛查效用。纳入年龄大于18岁的缺血性或出血性卒中患者。在完成MoCA测试后一周内，通过电话联系每位患者的知情者（配偶、照护者等），并施测IQCODE简版。采用Cronbach's α、重测信度分析、探索性因子分析（EFA）和验证性因子分析（CFA）评估IQCODE简版的信度和结构效度。共纳入179例卒中患者（平均年龄：58.6 ± 13.7岁），其中18例（10%）为出血性卒中。IQCODE简版显示出极好的内部一致性（Cronbach's α = 0.94）。因子分析提示初步的四因子结构，解释总方差的76.5%。CFA证实模型拟合良好（RMSEA = 0.07，CFI = 0.973，TLI = 0.964）。对因子负荷的审查导致从初始模型中排除三个条目。16条目版本的ROC分析得出曲线下面积（AUC）为0.771（95% CI，0.70 - 0.84），最佳截断值为48.5（灵敏度：72.4%；特异度：71.1%）。精炼后的13条目版本在不损害灵敏度的情况下显示出改善的特异度（76%）。16条目版本和所提出的13条目IQCODE简版均显示出有前景的初步心理测量学特性，可作为有效的筛查工具。其电话施测的可行性及较强的心理测量学特性支持其在常规临床实践和远程筛查中的应用。
Abstract
Post-stroke cognitive impairment is frequently seen after stroke. We aimed to examine the psychometric properties, factorial structure, and screening utility of the IQCODE brief version in stroke patients using an informant-based approach to cognitive impairment screening. Patients aged older than 18 years with ischemic or hemorrhagic stroke were included. Within one week of completing the MoCA test, each patient's informant (spouse, caregiver, etc.) was contacted by phone, and the IQCODE brief version was administered. Cronbach's alpha, test-retest analysis, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA) were performed to assess the reliability and construct validity of the IQCODE brief version. A total of 179 patients with stroke (mean age: 58.6 ± 13.7 years) were included, 18 (10%) of them had hemorrhagic stroke. The IQCODE brief version demonstrated excellent internal consistency (Cronbach's alpha = 0.94). Factor analysis suggested a preliminary four-factor structure, explaining 76.5% of the total variance. CFA confirmed a good model fit (RMSEA = 0.07, CFI = 0.973, TLI = 0.964). Review of the factor loadings resulted in the exclusion of three items from the initial model. ROC analysis for the 16-item version yielded an area under the curve (AUC) of 0.771 (95% CI, 0.70 - 0.84), with an optimal cut-off score of 48.5 (sensitivity: 72.4%; specificity: 71.1%). A refined 13-item version demonstrated improved specificity (76%) without compromising sensitivity. Both the 16-item and the proposed 13-item IQCODE brief versions demonstrated promising preliminary psychometric properties, and they may serve as effective screening tools. Their feasibility for telephone administration and strong psychometric properties support their use in routine clinical practice and remote screening.
如何引用
AMA
Mine Sezgin, Edis Hacılar, Sevda Özel-Yıldız, Ozan Dörtkol, Esme Ekizoğlu, Nilüfer Yeşilot. IQCODE-Brief Version in Stroke Patients.. Brain and behavior. 2026; doi:10.1002/brb3.71649.
APA
Mine Sezgin, Edis Hacılar, Sevda Özel-Yıldız, Ozan Dörtkol, Esme Ekizoğlu, Nilüfer Yeşilot (2026). IQCODE-Brief Version in Stroke Patients.. Brain and behavior. https://doi.org/10.1002/brb3.71649
GB/T 7714
Mine Sezgin, Edis Hacılar, Sevda Özel-Yıldız, Ozan Dörtkol, Esme Ekizoğlu, Nilüfer Yeşilot. IQCODE-Brief Version in Stroke Patients.[J]. Brain and behavior, 2026 doi:10.1002/brb3.71649.
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