小肠浆膜表面的Walthard细胞巢模拟转移性癌：首例病例报告

摘要(中文译文)

瓦尔塔德细胞巢（Walthard cell nests，WCNs）是由尿路上皮样移行细胞构成的良性上皮增生性病变，最常见于女性生殖道及邻近腹膜表面。尽管通常为偶然发现，但罕见情况下可发生于生殖器外部位，且因其与转移性肿瘤相似而可能造成诊断困难。据我们所知，在回顾现有文献后，这是首例累及小肠浆膜表面的WCNs病例，患者为58岁男性，有尿路上皮癌病史，因绞窄性脐疝就诊。术中观察到多个小肠浆膜小结节，令人担忧转移性疾病。组织病理学检查结合免疫组化证实了WCNs的诊断。本病例扩展了WCNs已报道的解剖部位范围，并强调了识别这一良性病变以避免误诊为转移性疾病的重要性。

Abstract

Walthard cell nests (WCNs) are benign epithelial proliferations composed of urothelial-like transitional cells, most commonly encountered within the female reproductive tract and adjacent peritoneal surfaces. Although typically incidental findings, they may rarely occur in extragenital locations and can pose a diagnostic challenge due to their resemblance to metastatic tumors. To the best of our knowledge, following a review of the available literature, this is the first case of WCNs involving the serosal surface of the small intestine in a 58-year-old male patient with a history of urothelial carcinoma who presented with a strangulated umbilical hernia. Multiple small serosal nodules observed intraoperatively raised concern for metastatic disease. Histopathologic examination with immunohistochemistry confirmed the diagnosis of WCNs. This case expands the spectrum of reported anatomical locations of WCNs and highlights the importance of recognizing this benign entity to avoid misdiagnosis as metastatic disease.

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