椎旁肌肉与骨密度关系的诊断视角：一项叙述性综述
Diagnostic Perspectives on the Relationship Between Paraspinal Muscles and Bone Mineral Density: A Narrative Review.
摘要(中文译文)
随着全球人口老龄化，骨质疏松症及相关的椎体压缩性骨折日益普遍。尽管骨密度（BMD）仍是诊断骨质疏松症的标准临床参数，但其对脊柱整体骨健康的评估并不全面。椎旁肌对脊柱稳定性和运动至关重要。本叙述性综述旨在评估椎旁肌状态与腰椎骨密度之间的相互作用，从而为全面的骨健康管理提供科学依据。在PubMed中使用相关关键词进行了全面的文献检索，以识别评估椎旁肌与骨密度之间功能和形态学相互作用的研究。现有证据表明，椎旁肌脂肪浸润（FI）与腰椎骨密度之间存在显著的负相关。高FI被确定为骨质疏松性椎体骨折的独立危险因素，也是术后并发症的有力预测指标。椎旁肌横截面积（CSA）与BMD之间的关系仍存在争议。然而，有针对性的高冲击和抗阻训练通过肌肉收缩产生显著的机械负荷，为保留骨小梁BMD提供生物学刺激。证据强调了椎旁肌状态与骨密度之间的关键协同作用，其中肌肉脂肪浸润是骨丢失和骨折易感性的关键标志物。将这些肌肉参数与传统的BMD测量相结合，可改善骨折风险分层和骨质疏松症管理。
Abstract
With the global population aging, osteoporosis and associated vertebral compression fractures are increasingly prevalent. While bone mineral density (BMD) remains the standard clinical parameter for diagnosing osteoporosis, it provides an incomplete assessment of holistic spinal bone health. Paraspinal muscles are essential for spinal stability and movement. This narrative review aims to evaluate the interplay between paraspinal muscle status and lumbar spine BMD, thereby providing a scientific foundation for comprehensive bone health management. A comprehensive literature search was conducted in PubMed using relevant keywords to identify studies evaluating the functional and morphological interactions between paraspinal muscles and bone mineral density. Current evidence demonstrates a significant negative correlation between paraspinal muscle FI and lumbar spine BMD. High FI is identified as an independent risk factor for osteoporotic vertebral fractures and a robust predictor of postoperative complications. The relationship between paraspinal muscle CSA and BMD remains debated. Nevertheless, targeted high-impact and resistance training generate substantial mechanical loading through muscle contraction, providing biological stimuli for trabecular BMD preservation. Evidence highlights a critical synergy between paraspinal muscle status and bone mineral density, with muscle fat infiltration acting as a key marker for bone loss and fracture susceptibility. Integrating these muscle parameters with traditional BMD measurements improves fracture risk stratification and osteoporosis management.
如何引用
AMA
Hui Liu, Moran Suo, Sinuo Yan, Qiwen Wang, Xin Chen, Zhonghai Li, et al. Diagnostic Perspectives on the Relationship Between Paraspinal Muscles and Bone Mineral Density: A Narrative Review.. Diagnostics (Basel, Switzerland). 2026; doi:10.3390/diagnostics16132010.
APA
Hui Liu, Moran Suo, Sinuo Yan, Qiwen Wang, Xin Chen, Zhonghai Li, et al (2026). Diagnostic Perspectives on the Relationship Between Paraspinal Muscles and Bone Mineral Density: A Narrative Review.. Diagnostics (Basel, Switzerland). https://doi.org/10.3390/diagnostics16132010
GB/T 7714
Hui Liu, Moran Suo, Sinuo Yan, Qiwen Wang, Xin Chen, Zhonghai Li, et al. Diagnostic Perspectives on the Relationship Between Paraspinal Muscles and Bone Mineral Density: A Narrative Review.[J]. Diagnostics (Basel, Switzerland), 2026 doi:10.3390/diagnostics16132010.
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