具有罕见临床特征的腭部先天性黑色素细胞痣：一例罕见病例报告及文献复习
Palatal Congenital Melanocytic Nevus With Unusual Clinical Feature: A Rare Case Report With Literature Review.
摘要(中文译文)
先天性黑色素细胞痣是一种不常见的良性病变，主要累及皮肤，在口腔内极为罕见，其非典型表现因与其他色素性病变存在临床重叠而可能带来诊断挑战。我们报告一例发生于34岁女性腭部黏膜内的先天性黑色素细胞痣（CMN），患者表现为一自出生起即存在的腭部色素区域上出现的无痛性结节性病变。组织病理学检查显示痣细胞良性增生并形成痣细胞巢。最深的痣细胞邻近相邻的小唾液腺小叶。该病变经完整手术切除处理，6个月随访时愈合良好。对文献的全面回顾仅发现11例已报道的口腔内CMN病例，证实腭部是最常受累的部位，且女性明显占优势。本例强调了将临床病史与组织病理学发现相关联以实现准确诊断的关键作用。
Abstract
Congenital melanocytic nevi are uncommon benign lesions that primarily involve the skin and are exceedingly rare within the oral cavity, where their atypical presentation may pose a diagnostic challenge due to clinical overlap with other pigmented lesions. We report a case of an intramucosal palatal congenital melanocytic nevus (CMN) in a 34-year-old woman who presented with a painless nodular lesion arising from a lifelong pigmented area of the palate. Histopathological examination demonstrated a benign proliferation of nevus cells with theques formation. The deepest nevus cells showed proximity to the adjacent minor salivary gland lobules. The lesion was managed by complete surgical excision, with uneventful healing at 6-month follow-up. A comprehensive review of the literature identified only 11 reported cases of intraoral CMNs, confirming the palate as the most frequently involved site and a marked female predominance. This case highlights the critical role of correlating clinical history with histopathological findings to achieve an accurate diagnosis.
如何引用
AMA
Saede Atarbashi-Moghadam, Ali Lotfi, Mohammadreza Kashefi Baher. Palatal Congenital Melanocytic Nevus With Unusual Clinical Feature: A Rare Case Report With Literature Review.. Clinical case reports. 2026; doi:10.1002/ccr3.73101.
APA
Saede Atarbashi-Moghadam, Ali Lotfi, Mohammadreza Kashefi Baher (2026). Palatal Congenital Melanocytic Nevus With Unusual Clinical Feature: A Rare Case Report With Literature Review.. Clinical case reports. https://doi.org/10.1002/ccr3.73101
GB/T 7714
Saede Atarbashi-Moghadam, Ali Lotfi, Mohammadreza Kashefi Baher. Palatal Congenital Melanocytic Nevus With Unusual Clinical Feature: A Rare Case Report With Literature Review.[J]. Clinical case reports, 2026 doi:10.1002/ccr3.73101.
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