东南部正番茄斑萎病毒属病毒中媒介生物学、传播与基因组结构的关联
Linking vector biology, transmission, and genome architecture in southeastern orthotospoviruses.
摘要(中文译文)
正托孢病毒（Orthotospoviruses）通过蓟马介导的持久增殖型传播，持续对美国东南部的特色作物和行栽作物构成重大威胁。本文综合阐述了番茄斑萎病毒（TSWV）和大豆叶脉坏死病毒（SVNV）的发生与生物学特性，并结合凤仙花坏死斑病毒、花生环斑病毒和番茄褪绿斑病毒（TCSV）的相关背景进行讨论。TSWV寄主范围广泛且具有全球重要性，而SVNV已知寄主范围较窄，但仍在各大豆产区持续扩展。比较基因组分析提示二者具有不同的进化模式：TSWV在S和M片段的基因间区表现出更大的结构可塑性，而SVNV则保留了更为保守的基因间区架构和发夹结构。这些差异为比较正托孢病毒的发生提供了框架，但其流行病学意义在不同病毒—媒介系统中仍未能得到均衡阐明。防控策略同样出现分化：番茄和辣椒中的单基因抗性屡次被克服抗性的TSWV变异株所突破，而靶向全部五个病毒开放阅读框的多基因发夹结构构建体则对TSWV和TCSV提供更广泛的保护。综合而言，这些比较揭示了基因组架构和媒介生物学如何塑造美国东南部正托孢病毒的发生与防控。
Abstract
Orthotospoviruses remain major threats to specialty and row crops in the southeastern United States through thrips-borne, persistent-propagative transmission. We synthesize the emergence and biology of tomato spotted wilt virus (TSWV) and soybean vein necrosis virus (SVNV), with context from impatiens necrotic spot virus, groundnut ringspot virus, and tomato chlorotic spot virus (TCSV). TSWV has a broad host range and global importance, whereas SVNV has a narrower known host range but continues to expand across soybean-producing regions. Comparative genomic analyses suggest distinct evolutionary patterns: TSWV shows greater structural plasticity in the S and M segment intergenic regions, whereas SVNV retains more conserved intergenic architectures and hairpin structures. These differences provide a framework for comparing orthotospovirus emergence, but their epidemiological significance remains unevenly resolved across virus-vector systems. Management has likewise diverged, with single-gene resistance in tomato and pepper repeatedly overcome by resistance-breaking TSWV variants, while multigenic hairpin constructs targeting all five viral ORFs provide broader protection against TSWV and TCSV. Together, these comparisons highlight how genome architecture and vector biology shape orthotospovirus emergence and management in the Southeast.
如何引用
AMA
Abdelaal Ha Shehata, Edward J Sikora, Amanda Strayer-Scherer, Kathleen M Martin. Linking vector biology, transmission, and genome architecture in southeastern orthotospoviruses.. Current opinion in virology. 2026; doi:10.1016/j.coviro.2026.101565.
APA
Abdelaal Ha Shehata, Edward J Sikora, Amanda Strayer-Scherer, Kathleen M Martin (2026). Linking vector biology, transmission, and genome architecture in southeastern orthotospoviruses.. Current opinion in virology. https://doi.org/10.1016/j.coviro.2026.101565
GB/T 7714
Abdelaal Ha Shehata, Edward J Sikora, Amanda Strayer-Scherer, Kathleen M Martin. Linking vector biology, transmission, and genome architecture in southeastern orthotospoviruses.[J]. Current opinion in virology, 2026 doi:10.1016/j.coviro.2026.101565.
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