睡眠障碍手法治疗的全球趋势和神经生物学前沿:将文献计量学与临床证据相结合
Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence.
Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence.
睡眠障碍不仅损害夜间休息,还显著影响日间功能、情绪调节和整体心理健康。除传统药物治疗外,手法治疗已成为一种有前景的非药物干预手段。具体而言,新出现的证据表明其益处可能延伸至缓解心理困扰和改善情绪。本研究采用文献计量学方法,系统探讨手法治疗睡眠障碍的研究现状、研究热点和未来趋势,重点关注其心理生理学结局。从Web of Science核心合集(WoSCC)检索与手法治疗睡眠障碍相关的文献,使用VOSviewer和CiteSpace进行文献计量学可视化与分析。此外,提取PubMed中的临床试验记录,以评估该领域的转化与临床进展。分析共纳入来自63个国家321个机构的594篇文献。总体趋势显示,发文量和引用影响力均呈持续年度增长,反映出学术关注度不断上升。关键词和文献共现分析表明,探索神经生物学机制和昼夜节律调控是主要研究前沿。文献计量学证据表明,手法治疗睡眠障碍的研究正朝着多维度和跨学科整合的方向发展。手法治疗日益成为一种关键的补充治疗手段,通过调节5-羟色胺(5-HT)和下丘脑-垂体-肾上腺轴(HPA轴)发挥治疗作用。其安全性和有效性构成明显优势;然而,未来的临床转化需要多中心验证和标准化的假对照方案。
Sleep disorders not only impair nocturnal rest but also significantly compromise daytime functioning, emotional regulation, and overall mental well-being. Beyond conventional pharmacological treatments, manual therapy has emerged as a promising non-pharmacological intervention. Specifically, emerging evidence suggests its benefits may extend to alleviating psychological distress and enhancing mood. This study employs a bibliometric approach to systematically investigate the current status, research hotspots, and future trends of manual therapy for sleep disorders, with an emphasis on its psycho-physiological outcomes. Publications related to manual therapy for sleep disorders were retrieved from the Web of Science Core Collection (WoSCC). Bibliometric visualizations and analyses were conducted using VOSviewer and CiteSpace. Furthermore, clinical trial records from PubMed were extracted to assess the translational and clinical advancements in this field. The analysis included 594 publications originating from 321 institutions across 63 countries. The overall trend demonstrates a consistent annual increase in both publication volume and citation impact, reflecting escalating academic interest. Keyword and literature co-occurrence analyses indicate that exploring neurobiological mechanisms and circadian rhythm regulation are the predominant research frontiers. Bibliometric evidence indicates that research on manual therapy for sleep disorders is evolving toward multidimensional and interdisciplinary integration. Manual therapy increasingly emerges as a key complementary treatment, exerting therapeutic effects via the regulation of 5-hydroxytryptamine (5-HT) and the Hypothalamic-Pituitary-Adrenal axis (HPA axis). Its safety and efficacy represent distinct advantages; however, future clinical translation necessitates multi-center validation and standardized sham-controlled protocols.
Yixiang Wang, Donghai Wu, Yingjun Liu, Siying Qu, Yutian Chen, Huiqin Chu, et al. Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence.. Frontiers in psychiatry. 2026; doi:10.3389/fpsyt.2026.1863957.
Yixiang Wang, Donghai Wu, Yingjun Liu, Siying Qu, Yutian Chen, Huiqin Chu, et al (2026). Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence.. Frontiers in psychiatry. https://doi.org/10.3389/fpsyt.2026.1863957
Yixiang Wang, Donghai Wu, Yingjun Liu, Siying Qu, Yutian Chen, Huiqin Chu, et al. Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence.[J]. Frontiers in psychiatry, 2026 doi:10.3389/fpsyt.2026.1863957.
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