秦岭自由活动犬中细小病毒的监测及跨物种传播至大熊猫的风险评估
Surveillance of Parvovirus in Free-Roaming Dogs in the Qinling Mountains and Assessment of the Risk of Cross-Species Transmission to Giant Pandas.
摘要(中文译文)
为评估佛坪国家级自然保护区内自由 roaming犬向野生大熊猫跨物种传播犬细小病毒（CPV）的风险，我们于2024年8月至2025年8月按季节采集了犬的直肠拭子和血清样本以及大熊猫的粪便样本，并结合种群调查和GPS家域追踪。犬的疫苗接种覆盖率从54.2%下降至36.4%，而易感犬比例从8.7%上升至29.5%。犬CPV核酸阳性率为3.9%（4/102，均为亚成年犬，其中三例死亡），而所有大熊猫样本均为阴性。基于个体-季节暴露计算，血清暴露率为30.4%，未成熟犬的风险显著高于成年犬（OR = 5.37）。犬与大熊猫的家域重叠（95% KDE：寒冷季节为19.17%，温暖季节为2.61%）及相遇概率在冬季和春季明显更高。犬源CPV毒株具有感染大熊猫的分子潜力。综上，CPV在自由 roaming犬群中长期持续存在，夏季疫苗接种未能建立有效的免疫屏障，冬春季是跨物种传播的高风险窗口期。我们建议加强冬春季免疫接种、空间管控措施以及外来犬只的检疫规程。
Abstract
To assess the risk of cross-species transmission of canine parvovirus (CPV) from free-roaming dogs to wild giant pandas in the Foping National Nature Reserve, we collected rectal swabs and serum samples from dogs and fecal samples from giant pandas seasonally (August 2024-August 2025), combined with population surveys and GPS home-range tracking. Vaccination coverage declined from 54.2% to 36.4%, while the proportion of susceptible dogs rose from 8.7% to 29.5%. The CPV nucleic acid positive rate in dogs was 3.9% (4/102, all sub-adults, three deaths), whereas all giant panda samples were negative. Based on individual-seasonal exposure, the serum exposure rate was 30.4%, with immature dogs at significantly higher risk than adults (OR = 5.37). Home-range overlap between dogs and giant pandas (95% KDE: 19.17% in cold seasons vs. 2.61% in warm seasons) and encounter probability were markedly higher in winter and spring. Canine-derived CPV strains possessed the molecular potential to infect giant pandas. In summary, CPV persists long-term in free-roaming dog populations, summer vaccination has not established an effective immune barrier, and winter-spring is a high-risk window for cross-species transmission. We recommend enhanced winter-spring immunization, spatial control measures, and quarantine protocols for incoming dogs.
如何引用
AMA
Zhiyang Huang, U Cheong, Zichen Liu, Jiao He, Leigang Zhao, Dapeng Zhu, et al. Surveillance of Parvovirus in Free-Roaming Dogs in the Qinling Mountains and Assessment of the Risk of Cross-Species Transmission to Giant Pandas.. Animals : an open access journal from MDPI. 2026; doi:10.3390/ani16111686.
APA
Zhiyang Huang, U Cheong, Zichen Liu, Jiao He, Leigang Zhao, Dapeng Zhu, et al (2026). Surveillance of Parvovirus in Free-Roaming Dogs in the Qinling Mountains and Assessment of the Risk of Cross-Species Transmission to Giant Pandas.. Animals : an open access journal from MDPI. https://doi.org/10.3390/ani16111686
GB/T 7714
Zhiyang Huang, U Cheong, Zichen Liu, Jiao He, Leigang Zhao, Dapeng Zhu, et al. Surveillance of Parvovirus in Free-Roaming Dogs in the Qinling Mountains and Assessment of the Risk of Cross-Species Transmission to Giant Pandas.[J]. Animals : an open access journal from MDPI, 2026 doi:10.3390/ani16111686.
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