替拉敏-唑拉西泮在异国宠物和野生动物麻醉中的使用：对实用指南的叙述性综述
Tiletamine-Zolazepam Use in Exotic Pets and Wildlife Anesthesia: A Narrative Review Towards Practical Guidelines.
摘要(中文译文)
本叙述性综述探讨了替来他明-唑拉西泮（tiletamine-zolazepam，TZ）在异宠及野生动物麻醉中的临床应用，并阐述了在管理涵盖广泛分类谱系、具有多样生理特征和性情差异的动物时所固有的复杂性。作为一种固定剂量复方制剂，TZ是实现平衡麻醉的多模式方案中的基石。其冻干制剂可用多种镇静溶液复溶，便于低容量给药，这是野生动物和小型异宠制动的一项关键要求。鉴于物种特异性反应和环境影响因素存在显著差异，选择和调整合适的TZ方案对从业者而言仍是一项挑战。本综述通过将异质性数据整合为经专家验证的指导意见，为专科和全科兽医提供了合理使用TZ的实用考量。重点在于将TZ整合于多模式方案中，以降低觉醒风险、确保稳定的制动并促进快速恢复。该方法旨在优化麻醉效果，并促进这些生理多样性群体的动物福利。
Abstract
This narrative review examines the clinical application of tiletamine-zolazepam (TZ) in exotic pet and wildlife anesthesia, addressing the complexities inherent in managing a broad taxonomic spectrum with diverse physiological profiles and temperaments. As a fixed-dose combination, TZ is a cornerstone of multimodal protocols designed to achieve balanced anesthesia. Its lyophilized formulation permits reconstitution with various sedative solutions, facilitating low-volume administration, a critical requirement for the immobilization of wildlife and small exotic patients. Given the significant variability in species-specific responses and environmental influences, selecting and adapting appropriate TZ-based protocols remain a challenge for practitioners. By synthesizing heterogeneous data into expert-validated guidance, this review provides specialized and general veterinarians with practical considerations for the judicious use of TZ. Emphasis is placed on integrating TZ within multimodal protocols to mitigate arousal risks, ensure consistent immobilization, and facilitate rapid recovery. This approach seeks to optimize anesthetic outcomes and promote animal welfare across these physiologically diverse populations.
如何引用
AMA
Emmanuel Risi, Romain Potier, Carsten Grøndahl, Laure Poincelot. Tiletamine-Zolazepam Use in Exotic Pets and Wildlife Anesthesia: A Narrative Review Towards Practical Guidelines.. Animals : an open access journal from MDPI. 2026; doi:10.3390/ani16091300.
APA
Emmanuel Risi, Romain Potier, Carsten Grøndahl, Laure Poincelot (2026). Tiletamine-Zolazepam Use in Exotic Pets and Wildlife Anesthesia: A Narrative Review Towards Practical Guidelines.. Animals : an open access journal from MDPI. https://doi.org/10.3390/ani16091300
GB/T 7714
Emmanuel Risi, Romain Potier, Carsten Grøndahl, Laure Poincelot. Tiletamine-Zolazepam Use in Exotic Pets and Wildlife Anesthesia: A Narrative Review Towards Practical Guidelines.[J]. Animals : an open access journal from MDPI, 2026 doi:10.3390/ani16091300.
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