微塑料明显调节玉米中镉的积累和脂质稳态：从膜重塑到基因表达的机制见解
Microplastics distinctly regulate cadmium accumulation and lipid homeostasis in maize: Mechanistic insights from membrane remodeling to gene expression.
摘要(中文译文)
源自地膜覆盖的微塑料（MPs）普遍存在于镉（Cd）污染的农业土壤中，但其对Cd植物毒性的影响仍存在争议。脂质重塑是植物胁迫响应的关键过程，但常规与可生物降解微塑料在Cd胁迫下是否差异调控该过程尚不清楚。本研究通过为期35天的盆栽试验，比较了两种浓度（0.1%和1%）的常规聚乙烯（PE）和可生物降解聚乳酸（PLA）微塑料对玉米Cd植物毒性的影响，主要聚焦于脂质稳态。微塑料与Cd的单次及复合暴露均抑制了玉米生长和光合作用，并诱导了氧化胁迫。PE显著降低了地上部和根部Cd浓度（20.06-38.71%）及吸收量（27.22-39.77%）。PLA表现出剂量依赖性效应，0.1%添加量增加了根部Cd积累，而1%添加量降低了地上部Cd积累。这些效应可能归因于必需矿质元素（Ca、Fe和Cu）稳态的改变。交互作用分析表明，PE在0.1%时与Cd呈拮抗作用，在1%时呈协同作用，而PLA在两种浓度下均表现为拮抗作用。整合脂质组学和转录组学分析鉴定出五个关键调控基因（LACS4、GPAT6、LPP2、PLA2-III和LPCAT4），其与36种甘油磷脂和甘油脂质显著相关，揭示了PE和PLA在Cd胁迫下通过不同的脂质代谢途径影响玉米的分子响应。这些发现表明，常规和可生物降解微塑料通过脂质重塑差异调控Cd污染土壤中的Cd植物毒性，为农膜覆盖的安全性评估提供了新见解。
Abstract
Microplastics (MPs) derived from film mulching commonly exist in cadmium (Cd)-contaminated agricultural soil, but their impacts on Cd phytotoxicity are still controversial. Lipid remodeling is a key plant stress response, but whether conventional and biodegradable MPs differently regulate this process under Cd stress remain unclear. This study compared the effects of conventional polyethylene (PE) and biodegradable polylactic acid (PLA) MPs at two concentrations (0.1% and 1%) on Cd phytotoxicity in maize via a 35-day pot experiment, mainly focusing on the lipid homeostasis. Both individual and combined exposures to MPs and Cd inhibited maize growth and photosynthesis and induced oxidative stress. PE significantly reduced Cd concentration (20.06-38.71%) and uptake content (27.22-39.77%) in shoots and roots. PLA exhibited dose-dependent effects, where 0.1% addition increased Cd accumulation in roots, while 1% addition decreased it in shoots. These effects might be attributed to altered homeostasis of essential minerals (Ca, Fe, and Cu). Interaction analysis revealed that PE acted antagonistically with Cd at 0.1% and synergistically at 1%, while PLA showed antagonism at both concentrations. Integrated lipidomic and transcriptomic analyses identified five key regulatory genes (LACS4, GPAT6, LPP2, PLA2-III, and LPCAT4) significantly associated with 36 glycerophospholipids and glycerolipids, revealing that PE and PLA influenced maize molecular response via distinct lipid metabolism pathways under Cd stress. These findings demonstrate that conventional and biodegradable MPs differentially regulate Cd phytotoxicity in Cd‑contaminated soils through lipid remodeling, providing new insights for the safety assessment of agricultural film mulching.
如何引用
AMA
Huijun Li, Xiaodie Zheng, Honghong Shan, Yichao Huang, Chuanxin Ma, Jian Zhao, et al. Microplastics distinctly regulate cadmium accumulation and lipid homeostasis in maize: Mechanistic insights from membrane remodeling to gene expression.. Journal of hazardous materials. 2026; doi:10.1016/j.jhazmat.2026.142486.
APA
Huijun Li, Xiaodie Zheng, Honghong Shan, Yichao Huang, Chuanxin Ma, Jian Zhao, et al (2026). Microplastics distinctly regulate cadmium accumulation and lipid homeostasis in maize: Mechanistic insights from membrane remodeling to gene expression.. Journal of hazardous materials. https://doi.org/10.1016/j.jhazmat.2026.142486
GB/T 7714
Huijun Li, Xiaodie Zheng, Honghong Shan, Yichao Huang, Chuanxin Ma, Jian Zhao, et al. Microplastics distinctly regulate cadmium accumulation and lipid homeostasis in maize: Mechanistic insights from membrane remodeling to gene expression.[J]. Journal of hazardous materials, 2026 doi:10.1016/j.jhazmat.2026.142486.
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