美国成年人睡眠障碍与白内障之间的关联：一项横断面研究
Association between trouble sleeping and cataract in US adults: a cross-sectional study.
摘要(中文译文)
为探讨美国成年人中睡眠障碍与白内障之间的关联，鉴于全球白内障负担日益加重且睡眠问题高度流行。本横断面研究分析了2005-2008年美国国家健康与营养调查中2，601名年龄≥40岁成年人的数据。睡眠障碍通过自我报告的诊断进行评估，白内障状态通过自我报告的白内障手术史确定。多因素logistic回归模型对社会人口学因素、生活方式变量和合并症进行了校正。在调整所有协变量后，有睡眠障碍的参与者患白内障的比值比显著更高（OR=2.50，95% CI：1.35-4.62，=0.011）。亚组分析证实了该关联在不同人口学和临床特征中的稳健性，交互检验表明亚组之间无显著的效应修饰。睡眠障碍与美国成年人白内障比值比升高显著相关。这些发现提示将睡眠健康纳入白内障预防策略可能具有潜在价值。未来需要纵向研究来证实因果关系、探索潜在机制，并评估睡眠干预对白内障风险的影响。
Abstract
To investigate the association between trouble sleeping and cataract in US adults, given the increasing global burden of cataracts and the high prevalence of sleep problems. This cross-sectional study analyzed data from 2,601 adults aged ≥40 years in the National Health and Nutrition Examination Survey (2005-2008). Trouble sleeping was assessed through self-reported diagnosis, and cataract status was determined by self-reported history of cataract operation. Multiple logistic regression models were adjusted for sociodemographic factors, lifestyle variables, and comorbidities. Participants with trouble sleeping had significantly higher odds of cataracts (OR = 2.50, 95% CI: 1.35-4.62, = 0.011) after adjusting for all covariates. Subgroup analyses confirmed the robustness of this association across different demographic and clinical characteristics, with interaction tests indicating no significant effect modification between subgroups. Trouble sleeping was significantly associated with increased odds of cataracts in US adults. These findings suggest potential value in incorporating sleep health into cataract prevention strategies. Future longitudinal studies are needed to confirm causality, explore underlying mechanisms, and evaluate the impact of sleep interventions on cataract risk.
如何引用
AMA
Jun Huang, Yulan Zhang, Chao Wu, Chen Wu, Yifan Wu, Feiran Wang, et al. Association between trouble sleeping and cataract in US adults: a cross-sectional study.. Frontiers in medicine. 2026; doi:10.3389/fmed.2026.1535667.
APA
Jun Huang, Yulan Zhang, Chao Wu, Chen Wu, Yifan Wu, Feiran Wang, et al (2026). Association between trouble sleeping and cataract in US adults: a cross-sectional study.. Frontiers in medicine. https://doi.org/10.3389/fmed.2026.1535667
GB/T 7714
Jun Huang, Yulan Zhang, Chao Wu, Chen Wu, Yifan Wu, Feiran Wang, et al. Association between trouble sleeping and cataract in US adults: a cross-sectional study.[J]. Frontiers in medicine, 2026 doi:10.3389/fmed.2026.1535667.
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