CLINICAL OTOLARYNGOLOGY临床耳鼻咽喉头颈外科杂志（参考译名）
CLINICAL OTOLARYNGOLOGY(英文缩写 CLIN OTOLARYNGOL),ISSN 1749-4478,eISSN 1749-4486,中文译名:临床耳鼻咽喉头颈外科杂志（参考译名） 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-28 至 2026-09-28，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 2.729 | Q2 |
| 2022 | 2.100 | Q3 |
| 2023 | 1.700 | Q2 |
| 2024 | 1.500 | Q2 |
| 2025 | 1.900 | Q2 |
CLINICAL OTOLARYNGOLOGY 最新收录文献
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1. The Value of Systemic Immune-Inflammation Index in the Occurrence and Prognosis of Sudden Sensorineural Hearing Loss: A Meta-Analysis.
PMID:期刊:日期:2026-09-21Sudden sensorineural hearing loss (SSNHL) is a common otolaryngology emergency. This study aimed to evaluate the association of the systemic immune-inflammation index (SII) with the occurrence and prognosis of SSNHL. Systematic review and meta-analysis. Databases including PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, VIP, and SinoMed. A total of 1263 participants from 11 studies, comprising 716 SSNHL patients and 547 healthy controls. Weighted mean difference (WMD) and 95% confidence interval (CI) for SII levels. This meta-analysis included 11 studies involving 1263 participants, of whom 716 were SSNHL patients and 547 were healthy controls. The pooled results showed that SII was significantly higher in SSNHL patients than in healthy controls (WMD = 393.46, 95% CI: 222.02-564.91, p < 0.001). In addition, SII was significantly lower in the hearing recovery group than in the non-recovery group (WMD = -208.36, 95% CI: -412.27 to -4.34, p = 0.045). Elevated SII is associated with SSNHL occurrence and poorer hearing recovery. However, further prospective studies with adequate adjustment for confounders are required to clarify its independent prognostic value and clinical utility.
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2. Persistent Postural-Perceptual Dizziness in Older Adults: Associations With Intrinsic Capacity Decline, Probable Sarcopenia and Geriatric Syndromes.
2. 老年人持续性姿势-知觉性头晕：与内在能力下降、可能肌少症和老年综合征的关联PMID:期刊:日期:2026-09-20Persistent postural-perceptual dizziness (PPPD) is a chronic dizziness disorder in older adults, characterized by persistent non-vertiginous dizziness and postural instability. This study aimed to investigate the associations of intrinsic capacity, sarcopenia and geriatric syndromes with PPPD in older adults. This cross-sectional study included 263 individuals aged over 65 years (128 with PPPD and 135 without PPPD) attending geriatric and otorhinolaryngology outpatient clinics. PPPD was diagnosed according to Bárány Society criteria. Comprehensive geriatric assessment included intrinsic capacity domains, frailty (FRAIL scale), handgrip strength (HGS), sarcopenia parameters and history of falls. Multiple logistic regression models were constructed to evaluate independent associations while avoiding collinearity between overlapping variables. Separate models were used to assess physical performance, intrinsic capacity, sarcopenia and geriatric syndromes. Participants with PPPD had significantly lower intrinsic capacity, slower gait speed, lower handgrip strength, higher depressive symptoms, higher frailty and more frequent falls (all p ≤ 0.005). In locomotion-based models, slower gait speed (OR = 0.121, 95% CI: 0.031-0.474; p = 0.002), higher GDS-15 scores (OR = 1.131, 95% CI: 1.021-1.252; p = 0.018) and fall history (OR = 2.660, 95% CI: 1.502-4.711; p = 0.001) were independently associated with PPPD. In muscle strength models, lower handgrip strength was also associated with PPPD (OR = 0.927, 95% CI: 0.879-0.978; p = 0.006). Domain-based analysis showed that locomotor and psychological impairments were independently associated with PPPD. Lower intrinsic capacity was strongly associated with PPPD (OR = 0.497, 95% CI: 0.377-0.656; p < 0.001). In clinically oriented models, probable sarcopenia (OR = 2.185, 95% CI: 1.188-4.018; p = 0.012), frailty (OR = 2.381, 95% CI: 1.323-4.285; p = 0.004) and depression (OR = 2.558, 95% CI: 1.387-4.717; p = 0.003) were independently associated with PPPD, while malnutrition did not show a significant association. PPPD in older adults extends beyond a purely vestibular disorder, encompassing geriatric dimensions such as frailty, muscle weakness and depressive symptoms. An integrated otolaryngology-geriatrics care model is warranted, and longitudinal studies evaluating the impact of geriatric interventions on PPPD's natural history are needed.
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3. Nurse-Led Telephone Triage Clinic Service for Head and Neck Suspected cancer Referrals: A Prospective Study of 986 Referrals.
PMID:期刊:日期:2026-09-17Head and neck cancer (HNC) referral conversion in the UK is less than 3%. A nurse-led telephone assessment clinic (TAC) using the HaNC-RC v.2 triage tool was introduced to identify high-risk (HR) referrals. Prospective data were collected from all HNC referrals (n = 986) over 6 months, with descriptive analysis of TAC triage outcomes. Over 6 months, 986 referrals were reviewed, with a 4.4% (n = 43) cancer conversion rate. Of 483 (49.0%) TAC patients, 115 (23.8%) were high-risk (HR) triaged using the HaNC-RC v.2 tool. Cancer was diagnosed in 8 (7.0%) HR and 3 (0.9%) LR patients (early thyroid malignancies), who were subsequently upgraded to HR (p-value = < 0.001) with FDS compliance of 88% (95% CI: 83.5-92.1). Allowing for clinical capacity constraints, the first F2F clinical appointment with an HNC consultant was given to 63.1% of HR patients, and 7.7% of these patients were later confirmed to have cancer. HR and LR patients were seen within a mean of 9.2 and 10.2 days (p-value = 0.043), respectively. The mean waiting time was improved from 10.7 days (1st month) to 5.9 days (6th month) for an HR clinic slot (p-value = 0.04). This service evaluation study supports the use of the HaNC-RC v.2 at the 7.1% threshold in a TAC nurse-led clinic model alongside an STT pathway. The TAC service facilitated optimised use of consultant clinic slots, prioritising HR patients without compromising LR patients' outcomes and facilitated a reduction in USoC clinic slot requirements whilst helping FDS target compliance.
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4. Haemostatic Agent Use and Associated Complications After Thyroid Surgery: A Retrospective Cohort Study in a Tertiary Head and Neck Centre.
PMID:期刊:日期:2026-09-10Haemostatic agents are increasingly used in thyroid surgery to improve operative outcomes. Although randomised controlled trials (RCTs) have demonstrated benefits, their real-world efficacy is under-researched. To assess whether these agents may facilitate day-case thyroidectomies in the UK, this study evaluated postoperative outcomes associated with intraoperative application of topical haemostatic agents. A single-centre retrospective cohort study analysed patients aged ≥ 18 years who underwent elective thyroidectomies between May 2023 and May 2025. The primary outcome was the incidence of postoperative complications associated with intraoperative topical haemostatic agents, analysed using Fisher's exact test to compare patients who received haemostatic agents with those who did not. Secondary outcomes, including total drain output and length of inpatient stay, were analysed using the Mann-Whitney U test. In 167 thyroidectomies, haemostatic agents were used in 69 (41.3%) patients: oxidised regenerated cellulose in 41 operations (59.4%), fibrin sealants in 29 (42.0%), and both in one (1.6%). Overall, postoperative complications occurred in 37 (22%) patients. A significantly increased incidence of postoperative complications was observed with the use of haemostatic agents (p < 0.001; OR = 11.1; 95% CI, 2.69-50.5). No difference was observed in total drain output or length of stay between the two groups. In this cohort, postoperative complications were associated with the use of haemostatic agents, highlighting the challenge of observing RCT-demonstrated data in routine clinical practice. Further research with adjusted modelling is needed before determining the role of haemostatic agents in thyroid surgery. Until then, they cannot be relied upon to facilitate day-case thyroidectomies.
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5. Paediatric Voice Disorders in a Multidisciplinary Voice Clinic: A Retrospective Observational Study.
PMID:期刊:日期:2026-09-07Paediatric voice disorders encompass a broad diagnostic spectrum, but contemporary descriptions of multidisciplinary voice clinic case-mix, assessment and management remain limited. We performed a retrospective observational study of routinely collected clinical data from a quaternary multidisciplinary paediatric voice clinic in the United Kingdom. Children and adolescents aged 4-17 years who were seen between January 2024 and December 2025 were included. Patient-level variables included demographics, symptom duration, referral-to-first clinic waiting time, and primary diagnosis. Appointment-level variables included documentation of patient-reported outcome measures, endoscopic findings reported in clinic letters, management outcomes, and procedure follow-through. Of 111 listed appointments, 96 were attended (74 new and 22 follow-up) and 15 were non-attendances. These attended appointments represented 87 patients; median age at first appointment was 12 years (range 4-17 years), and 51/87 (58.6%) were male. Dysphonia was the main presenting symptom in 83/87 (95.4%). Median symptom duration at referral was 6.3 years (range 0.12-17.0 years), and median referral-to-first clinic waiting time was 154 days (range 16-1032 days). The most common diagnoses were vocal cord palsy (19/87, 21.8%), vocal cord nodules (11/87, 12.6%), and muscle tension dysphonia (9/87, 10.3%). In the vocal cord palsy/paresis subgroup (n = 20), 15/20 were left-sided and 13/20 were secondary to post-cardiac surgery/patent ductus arteriosus ligation. Children commonly experienced prolonged symptoms before specialist review, with a heterogeneous diagnostic spectrum and frequent vocal fold immobility. Standardised outcome capture and longer follow-up are needed to evaluate interventions and inform referral guidance.
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6. Olfactory Threshold Can Be Reliably Tested With Sniffin' Sticks in Non-Clinical Settings: Associations Shown in a Diverse, General Population.
PMID:期刊:日期:2026-09-07The olfactory threshold part of the Sniffin' Sticks test is widely used to assess chemosensory function, yet most studies are conducted in controlled laboratory or clinical environments with selective samples. This study examined odour threshold performance with the Sniffin' Sticks threshold test in a large, heterogenous sample, testing whether established associations generalise outside the lab. A total of 798 museum visitors aged 18-88 years completed the threshold test and rated their olfactory and gustatory ability, nasal patency, and sensitivity. Participants were classified as normosmic, hyposmic, or anosmic based on threshold scores. Associations with age, sex, health status, smoking, and alcohol use were analysed. Threshold performance was positively associated with self-rated chemosensory ability and negatively with age. Women showed higher performance, greater self-rated ability, and better nasal patency and sensitivity than men. Normosmic participants were younger and reported higher function than other groups, especially hyposmic individuals. Chronic illness and nasal problems were linked to poorer performance and lower self-ratings. Smoking related to lower self-rated olfactory ability but not threshold scores; self-rated alcohol use showed no effect. The prevalence of anosmia and hyposmia was comparable to epidemiological data. The Sniffin' Sticks threshold test provides a valid and practical tool for assessing olfactory sensitivity in naturalistic, non-clinical settings.
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7. Airway Intervention in Paediatric Angioedema: A National Analysis of Clinical Predictors and Outcomes.
PMID:期刊:日期:2026-09-01To characterize paediatric hospitalizations for angioedema and identify the prevalence and outcomes of airway interventions using a large national database. We performed a cross-sectional analysis of the Kids' Inpatient Database (2003-2019), including paediatric patients (0-20 years) hospitalized with angioedema identified by ICD-9/10 codes. Outcomes included hospital length of stay (LOS), total charges, and in-hospital mortality. Multivariable logistic regression evaluated predictors of airway intervention, and comparative analyses assessed outcome differences between patients with and without airway procedures. Among 4238 paediatric angioedema hospitalizations, 174 (4.1%) underwent airway procedures. Compared to non-intervention cases, these patients had significantly longer LOS (median 6 vs. 2 days, p < 0.001), higher charges ($59 571 vs. $7628, p < 0.001), and higher mortality (5.8% vs. 0.15%, p < 0.001). Black (adjusted odds ratio [AOR] 5.23, 95% CI 1.56-19.30) and Hispanic race (AOR 7.83, 95% CI 1.51-44.89) were associated with higher odds of intervention, while hospitalizations in the Northeast (AOR 0.10, 95% CI 0.015-0.55) and South (AOR 0.13, 95% CI 0.03-0.49) had lower odds compared to the Midwest. Airway interventions in paediatric angioedema are rare but linked to significantly higher morbidity, mortality, and healthcare costs. Geographic and racial disparities highlight the need to explore systemic factors shaping airway management decisions.
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8. Efficacy of Platelet-Rich Plasma in Post-Tonsillectomy Wound Healing and Pain Management: A Randomized Controlled Study.
PMID:期刊:日期:2026-09-01Tonsillectomy is one of the most common surgical procedures in otolaryngology, but the healing process remains unknown in individual patients. Several interventions, including platelet-rich plasma, have been investigated to improve healing and pain control due to their regenerative properties. To assess the effect of platelet-rich plasma injection during tonsillectomy on postoperative results especially on epithelization stage and postoperative pain. A prospective randomized controlled trial was conducted between January 2023 and December 2024, including 19 patients with platelet-rich plasma randomly injected in one of the fossae [treatment group] and normal saline in the other fossa [control group]. The endpoints were the epithelialization stage and pain score on days 1-7 after tonsillectomy. There were no statistically significant differences between groups in the postoperative epithelization stage. At the treatment sites, grade III wound epithelization was 21.1%, compared with the control site, where none had grade III wound epithelization. The p-values for wound epithelization (0.903) and pain score (0.222) indicate no difference between groups. Both groups' pain scores improved over time (p < 0.001). Intraoperative injection of platelet-rich plasma into the tonsillar beds was effective in stimulating tonsillar wound healing. Because of its properties, the treatment group appeared to have faster wound recovery than the control group. However, the differences were not statistically significant. Further studies with larger sample sizes are warranted to elucidate the potential benefits of platelet-rich plasma in post-tonsillectomy healing.
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9. Prognostic Analysis of Patients With N1 Nasopharyngeal Carcinoma With Different Lymph Node Characteristics.
PMID:期刊:日期:2026-09-01Prognosis in patients with N1 nasopharyngeal carcinoma (NPC) remains heterogeneous, partly due to variations in lymph node involvement. This study evaluated the prognostic significance of different lymph node characteristics in N1 NPC. We retrospectively analysed 160 newly diagnosed non-metastatic N1 NPC patients treated at Liuzhou Worker's Hospital from January 2017 to May 2023. Kaplan-Meier curves were used to estimate survival outcomes, and Cox regression analysis was performed to identify independent prognostic factors. Among the 160 patients, 57 had retropharyngeal lymph nodes (RLNs) only, 24 had cervical lymph nodes (CLNs) only, and 79 had concurrent CLNs and RLNs involvement. The 5-year overall survival (OS), progression-free survival (PFS), locoregional relapse-free survival (LRRFS), and distant metastasis-free survival (DMFS) rates were 94.7%, 80.1%, 89.6%, and 88.8%, respectively. Patients with concurrent CLNs and RLNs involvement had worse OS than those with single-region involvement (5-year OS: 90.2% vs. 98.4%, p = 0.0238). Subgroup analysis showed that in T1-2 patients, combined nodal involvement was associated with inferior OS, PFS, and LRRFS, whereas no significant survival differences were observed in T3-4 patients. Multivariate analysis identified lymph node necrosis (LNN) as an independent adverse prognostic factor for LRRFS (HR = 4.056; 95% CI: 1.262-13.035; p = 0.019). Lymph node characteristics further refine prognostic stratification in N1 NPC. Concurrent CLNs and RLNs involvement was associated with poorer survival, particularly in early T-stage disease, while LNN was associated with an increased risk of locoregional recurrence.
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10. Evaluation of the NHS R67 Monogenic Hearing Loss Panel in a Single UK Centre.
10. 英国单一中心对NHS R67单基因听力损失专家组的评估PMID:期刊:日期:2026-09-01The NHS R67 genetic hearing loss panel was introduced in England in 2021 and has expanded the diagnostic approach to hearing loss. This study aimed to evaluate the diagnostic yield and clinical utility of the panel in paediatric and adult patients assessed through a tertiary multidisciplinary genetic hearing loss clinic. A retrospective case review was conducted of patients referred to a tertiary genetic hearing loss multidisciplinary clinic who underwent R67 monogenic hearing loss analysis. Demographic data, referral patterns, family history, hearing loss severity, age at diagnosis, congenital cytomegalovirus testing, radiological findings, genetic results and hearing habilitation or rehabilitation strategies were analysed descriptively. Diagnostic yield was compared across hearing loss severity categories. Eighty-four patients were included, comprising 46 children and 38 adults. A monogenic diagnosis was identified in 48.8% of patients overall, with a higher yield in children than adults: 63.0% versus 31.6%, respectively. Variants of uncertain significance were identified in 7.1% of patients. Hearing loss severity was significantly associated with identification of a genetic cause, although 35% of patients with an identified genetic cause had mild or moderate hearing loss. The R67 monogenic hearing loss panel is a valuable diagnostic tool for investigating sensorineural hearing loss in children and adults, particularly when delivered through multidisciplinary clinics that support counselling and clinical decision-making. Further reporting is needed to refine referral criteria and support patient selection for targeted therapies.