PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE光皮肤病学、光免疫学与光医学
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE(英文缩写 PHOTODERMATOL PHOTO),ISSN 0905-4383,eISSN 1600-0781,中文译名:光皮肤病学、光免疫学与光医学 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 3.254 | Q2 |
| 2022 | 2.600 | Q2 |
| 2023 | 2.500 | Q2 |
| 2024 | 2.200 | Q2 |
| 2025 | 2.700 | Q2 |
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE 最新收录文献
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1. Comparative Efficacy and Safety of Needling-Based Therapies Versus Ablative Fractional Lasers for Scar Management: A Systematic Review and an Exploratory Meta-Analysis.
PMID:日期:2026-09-01Needling-based therapies and ablative fractional lasers are widely used for scar management, but their efficacy and safety remain uncertain. In this systematic review, we aimed to assess the safety and efficacy of both needling-based therapy and ablative fractional laser therapy. This review followed PRISMA 2020 and the Cochrane Handbook. PubMed, Scopus, Web of Science, and Cochrane were searched from inception to 9 April 2026 without restrictions. Studies enrolling patients with scars of any etiology and comparing a needling-based therapy with an ablative fractional laser were included. Randomized controlled trials (RCTs), non-randomized trials, and cohort studies were eligible. Risk of bias was assessed using RoB 2, ROBINS-I, and the Newcastle-Ottawa Scale. Because of heterogeneity, findings were synthesized narratively, with exploratory random-effects meta-analysis where data were sufficiently comparable. Twenty-seven studies involving 1137 participants were included, comprising 17 RCTs, 2 non-randomized comparative trials, and 8 cohort studies. Most studies evaluated atrophic or hypertrophic acne scars (18 studies; 870 patients), while fewer studies assessed striae (4 studies; 87 patients), burn or postburn scars (3 studies; 105 patients), and traumatic scars (2 studies; 75 patients). Both treatment categories improved scar appearance. In many comparisons of atrophic acne scars, ablative fractional lasers, particularly fractional CO and, in some studies, Er:YAG systems, suggested greater improvement than microneedling. However, needling-based therapies were associated with shorter downtime, better tolerability, and fewer pigmentary adverse effects. Microneedling radiofrequency appeared to provide efficacy closer to that of ablative lasers in several individual studies and demonstrated a more favorable safety profile. Recent combination regimens appeared promising. Available evidence suggests that both modalities can improve scars. Ablative fractional lasers may offer greater efficacy, whereas needling-based therapies may provide better tolerability and pigment safety. These conclusions should be interpreted cautiously because of clinical heterogeneity and the sensitivity of the exploratory pooled estimate to individual studies. Treatment selection should remain individualized according to scar type, patient priorities, and acceptable downtime. The protocol was registered in PROSPERO (CRD420261383840).
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2. Photothermal-Activated Platelet-Rich Plasma Versus Conventional Platelet-Rich Plasma for Melasma: A Split-Face, Double-Blind Randomized Controlled Trial.
PMID:日期:2026-09-01Melasma is a common acquired pigmentary disorder that predominantly affects women with darker skin types and substantially impairs quality of life. Current treatments are limited by variable efficacy, adverse effects, and frequent recurrence. Platelet-rich plasma (PRP) has emerged as a potential regenerative treatment through growth-factor-mediated modulation of melanogenesis. Photothermal activation, which combines photobiomodulation with controlled hypothermic conditioning, has been hypothesized to promote a more sustained growth-factor release than conventional PRP. This study compared the efficacy and safety of photothermal-activated PRP (PT-PRP) and conventional PRP (C-PRP) for melasma treatment. This split-face, double-blind, randomized controlled trial included 26 women with epidermal or mixed-type melasma. Each participant received three monthly sessions of intradermal PRP, with PT-PRP and C-PRP injected into opposite facial sides. Outcomes were assessed at weeks 0, 4, 8, and 12 using the modified Melasma Area and Severity Index (mMASI), Mexameter melanin and erythema indices, patient satisfaction, overall improvement, and adverse events. Both treatments significantly reduced mMASI by week 12, with no significant between-group differences at any time point. C-PRP showed significant mMASI improvement from week 4, whereas PT-PRP reached significance from week 8. For the melanin index, PT-PRP produced a significant within-group reduction at week 12, while C-PRP did not. At week 12, PT-PRP showed a significantly lower melanin index than C-PRP. Mild injection-site bruising was the only adverse event. PT-PRP and C-PRP produced comparable clinical improvement, but PT-PRP achieved greater objective melanin reduction at week 12. PT-PRP may represent a safe alternative treatment for melasma. Thai Clinical Trials Registry: TCTR20260318004.
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4. Persistent PhytoPhotoDermatitis Without Repeated Phytotoxin Exposure.
PMID:日期:2026-09-01该文献暂无摘要。
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5. Sun Exposure and Photoprotection Knowledge, Habits, and Attitudes Among Spanish Military Personnel.
PMID:日期:2026-09-01The incidence of skin cancer continues to rise, with ultraviolet (UV) radiation exposure representing its main modifiable risk factor. Military personnel constitute a particularly vulnerable population due to the combination of occupational and recreational sun exposure, together with operational constraints related to uniforms and working conditions. The aim of this study was to assess knowledge, habits, and attitudes related to sun exposure and photoprotection among Spanish military personnel, and to explore differences in photoprotective practices according to sociodemographic and professional variables. A cross-sectional observational study was conducted using a validated self-administered questionnaire in a sample of 500 active-duty Spanish military personnel from different ranks. Data collected included sociodemographic and phenotypic characteristics, knowledge, habits, and attitudes. Descriptive analyses and bivariate inferential analyses using non-parametric tests were performed. Most participants reported frequent sun exposure in both occupational and leisure settings, with longer daily exposure during leisure time; 81.6% reported exposure of ≥ 3 h per day. Overall, 73.4% experienced at least one sunburn in the previous year. Sunglasses and sunscreen were the most commonly adopted photoprotective measures, whereas avoidance of peak sun hours and use of protective clothing were infrequent. Knowledge of UV radiation risks was generally high, although misconceptions persisted regarding shade protection and vitamin D exposure. Photoprotective practices were significantly poorer during leisure time than during occupational activities (p < 0.01). Spanish military personnel demonstrate adequate knowledge and positive attitudes toward photoprotection but insufficient protective practices, particularly outside the occupational setting. These findings highlight the need to strengthen health education and integrate photoprotection into military training and operational environments.
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6. Evaluating the Efficacy of Sunscreen Formulas in Reducing UV Filter Permeation Into the Stratum Corneum via In Vivo Confocal Raman Spectroscopy: Insights and Applications for Practical Suncare Product Design.
PMID:日期:2026-09-01The transdermal permeation of UV filters has long been a concern among consumers and researchers. Among them, the permeation of small-molecule UV filters such as homosalate (HMS) (molecular weight < 500 Da) and the regulatory effects of formulation components on its permeation have not been fully investigated. Furthermore, sunscreen formulations containing skin brightening agents have become increasingly prevalent in recent years. Thus, verifying how to adjust formulation components to reduce UV filter permeation while not influencing the permeation of active ingredients such as the skin-brightening agent niacinamide is worthy of research. This study investigated the skin permeation of formulations containing HMS using an improved confocal Raman spectroscopy method. Among the tested UV filters, HMS exhibited the highest permeation, with a relative permeability rate of 4.2% and a maximum permeation depth of 60 μm. Subsequently, adjusting the proportion of components in the formulation indicated that thickeners (Carbomer and Acrylates/C10-30 Alkyl Acrylate Crosspolymer) and emulsifiers (PEG (Polyethylene Glycol)-100 Stearate/Glyceryl Stearate) could reduce the permeation of HMS, while the film-formers (VP (Vinylpyrrolidone)/Eicosene) had no impact on HMS permeation. Based on these findings, a real-life sunscreen formulation was designed and verified to reduce HMS permeation while ensuring effective skin permeation of niacinamide. The permeation of different single UV filters by confocal Raman spectroscopy suggested that HMS exhibited the deepest permeation. Subsequently, by designing a series of distinct formulations, we identified the formulation components that influence the permeation of HMS. Based on the study findings, a practical formulation was designed that not only minimizes the permeation of the UV filter (HMS) but also does not inhibit the permeation of the skin-brightening agent. This study may serve as a reference for subsequent investigations into the permeation of UV filters.
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7. Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence.
PMID:日期:2026-09-01Visible light (VL), and particularly high-energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes. As conventional sunscreens offer limited protection in the visible spectrum, increasing attention has been directed toward complementary photoprotective strategies, including the use of natural compounds with antioxidant and anti-inflammatory properties. This systematic review aims to evaluate and synthesize the available preclinical and clinical evidence on the photoprotective effects of natural compounds against VL-induced skin damage, emphasizing their mechanisms of action, efficacy, and safety. A comprehensive literature search was performed to identify studies reporting validated objective outcomes, including colorimetric parameters, diffuse reflectance spectroscopy, or clinical grading scales. Eligible studies were included, qualitatively synthesized, and risk of bias was evaluated. Preclinical studies demonstrated that natural compounds mitigated VL-induced oxidative stress, inflammation, and pigmentation-related pathways. Clinical studies showed that formulations containing natural compounds improved VL-induced erythema and pigmentation outcomes. However, considerable heterogeneity was observed in irradiation protocols, outcome measures, and study designs, precluding quantitative meta-analysis. Overall, available evidence supports a protective role for selected natural compounds against VL-induced skin damage, particularly through antioxidant and anti-inflammatory mechanisms, with the strongest clinical evidence focusing on natural sources of polyphenols. Nevertheless, this review highlights the need for standardized phototesting protocols and well-designed clinical trials. Future research should focus on comparative efficacy, long-term safety, and integration of natural compounds into combined photoprotection strategies tailored to different skin phototypes.
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9. Home Phototherapy for Psoriasis: Evidence and Implementation.
PMID:日期:2026-09-01Home phototherapy for psoriasis is non-inferior to office-based care, yet adoption remains limited by implementation barriers, inconsistent patient selection, and underrecognized safety gaps. This narrative review synthesizes recent evidence to address these gaps and provide actionable clinical guidance. PubMed and Embase were searched for studies published between January 1, 2020, and March 1, 2026, yielding 12 included studies. Study types included randomized controlled trials (RCTs), observational studies, cost analyses, implementation reports, and technical device comparisons; findings are interpreted by study design without formal risk-of-bias assessment. The LITE randomized trial demonstrates that home narrowband ultraviolet B (NB-UVB) phototherapy is non-inferior to office-based treatment in patients with plaque and guttate psoriasis, with high satisfaction, improved adherence, and reduced indirect costs. Erythema was the most common adverse event and rarely led to discontinuation; long-term safety data remain limited. Home phototherapy is safe and effective for appropriately selected patients with plaque or guttate psoriasis and represents an underutilized, cost-effective alternative to office-based care. This review identifies three gaps that must be addressed to realize its potential: absence of long-term UV exposure and skin cancer data, equity barriers that may paradoxically limit access for the patients who stand to benefit most, and uncharacterized safety risks of over-the-counter devices. Closing these gaps through prospective safety studies, equity-centered implementation, and regulatory oversight will be essential to establishing home phototherapy as a widely accessible, evidence-based standard of care.