AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE美国热带医学与卫生杂志
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE(英文缩写 AM J TROP MED HYG),ISSN 0002-9637,eISSN 1476-1645,中文译名:美国热带医学与卫生杂志 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 3.707 | Q2 |
| 2022 | 3.300 | Q1 |
| 2023 | 1.900 | Q2 |
| 2024 | 1.600 | Q3 |
| 2025 | 1.900 | Q3 |
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 最新收录文献
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2. Pulmonary Dirofilaria immitis Infection and Concurrent Pleural Lymphangiomatosis in a Young Woman from Costa Rica: A Diagnostic Challenge after 20 Years of Silence.
PMID:日期:2026-09-24Human dirofilariasis is an underreported, vector-borne disease caused by the filarioid Dirofilaria immitis. A case of pulmonary dirofilariasis is reported in a woman from Costa Rica, manifesting respiratory distress, marked eosinophilia of 47%, and severe chylothorax. Pleural biopsies revealed a lymphoplasmacytic reaction with eosinophils, and bronchoalveolar fluid analysis revealed 28S and internal transcribed spacer 1 fragments that were 100% and 99.3% similar to D. immitis, respectively, and a coxA sequence identical to Wolbachia from D. immitis. Other infectious, autoimmune, and malignant causes were excluded through an extensive diagnostic workup. Initial treatment included methylprednisolone, albendazole, and a subsequent course of albendazole plus doxycycline; however, the chylothorax recurred. A biopsy of the left upper lobe confirmed a pleural lymphangiomatosis. The patient was discharged with continued treatment but was clinically stable. This case reveals the diagnostic complexity of filariasis and underlying lymphadenopathies coexisting in endemic regions and highlights the value of an integrated clinical, molecular, and histopathological approach.
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3. Digitally Integrated Disease Management System in Rwanda: Community Healthcare Worker Perspectives.
PMID:日期:2026-09-24As digital health tools are increasingly deployed to support community-based primary healthcare, understanding frontline user experiences is critical for effective implementation and scale-up. Here, community health workers' (CHWs) perspectives on the digitally integrated disease management system (d-IDS) in Rwanda are discussed. The d-IDS intervention was intended to improve the cost-effectiveness of community-based screening, patient management, and disease surveillance through a mobile digital platform. Before implementation, user acceptance testing and cascade training prepared CHWs, their supervisors, and health facility staff. During implementation, continuous supervision and qualitative assessments of the system were conducted. Qualitative data were collected through focus group discussions and semi-structured key informant interviews. The CHWs widely appreciated the system's ease of use, comprehensiveness, availability in Kinyarwanda (local language), offline functionality, improved data management, and ability to expedite effective patient management cascades compared with paper-based registers. Home-based screening reduced patient time and costs of care and enhanced equity and access to care, bringing Rwanda closer to achieving Universal Healthcare Coverage. However, challenges included increased workload, inadequate or lack of incentives, internet connectivity constraints, system rigidity in updating household records, and initially low digital literacy among some CHWs. Ongoing digitalization initiatives will inform national scale-up and policy choices.
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4. Genetic Relatedness of Cambodian Plasmodium falciparum Isolates Was Associated with Geography and Occupation.
PMID:日期:2026-09-22Cambodia is nearing Plasmodium falciparum (P. falciparum) elimination, but targeted interventions are needed to prevent resurgence. Identity-by-descent (IBD)-based methods offer insight into parasite relatedness and transmission dynamics. Pairwise genetic relatedness was estimated among 107 P. falciparum isolates collected from military personnel and farmers during two clinical trials in Cambodia from 2014 to 2016. Using existing whole-genome sequence data, IBD relatedness was estimated as the proportion of the genome shared IBD between isolates. Associations between relatedness and epidemiological factors, including occupation, location, time, age, and sex, were evaluated. Network-based clustering was used to identify highly related isolate groups and associated covariates. High mean IBD sharing (40%) suggested clonal expansion or low transmission; isolates from Oddar Meanchey Province shared >20% more of their genome IBD than Kratie Province isolates (P <2.2e-16). Within Oddar Meanchey, isolates from individuals with different occupations shared 7.2% less of their genome IBD than farmer pairs (probability of direction [pd] = 0.999), after adjusting for age. Highly related clusters (>90% IBD) were associated with occupation, K13 mutation (C580Y versus R539T), and P. falciparum chloroquine resistance transporter mutation (P = 0.0027, 0.0001, and 0.0001, respectively). Isolates from mixed-occupation pairs had lower odds of being highly related (>90% IBD) than farmer pairs (pd = 0.958). High overall IBD sharing may reflect elimination efforts and the expansion of drug-resistant lineages. Differences in between-province relatedness underscore how geography shapes relatedness patterns. Lower relatedness among mixed-occupation pairs compared with farmer pairs suggests occupation-associated exposure differences, with occupation potentially acting as a proxy for micro-epidemiological exposure factors such as location or behavior, highlighting the need for locally tailored interventions.
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5. Absence of Plasmodium falciparum Histidine-Rich Protein 2 and 3 (Pfhrp2/3) Gene Deletions in Rizal, Palawan, the Philippines.
PMID:日期:2026-09-22Microscopy and rapid diagnostic tests (RDTs) are used in the Philippines as the gold standard for malaria diagnosis. However, parasites evading RDT detection have recently emerged in other settings as a result of deletions in Plasmodium falciparum histidine-rich protein genes (pfhrp2 and pfhrp3). Failure to detect and treat individuals carrying these deletions may result in increased malaria transmission and hinder elimination efforts. In addition to the implications for malaria elimination efforts, we emphasize that false-negative RDT results caused by pfhrp2/3 deletions pose a critical risk to patient outcomes, as individuals with active P. falciparum infections may go untreated. Sixty-three samples collected from Palawan, the Philippines, were interrogated for the presence of Plasmodium isolates and pfhrp deletions. All 63 samples were microscopically positive for P. falciparum. Although only 27 (43%) were positive for RDTs, all samples were confirmed free of pfhrp2 and pfhrp3 deletions by nested polymerase chain reaction (PCR) tests. RDT false negatives in the study were most likely caused by low parasite densities. Incorporating molecular monitoring of histidine-rich protein 2 deletions into routine malaria surveillance would improve assessments of the performance of the current RDTs and help strengthen strategies toward malaria elimination by 2030.
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6. Uterine Cervical Tuberculosis Mimicking Malignancy: Case Series from Ethiopia.
PMID:日期:2026-09-22Uterine cervical tuberculosis is a rare manifestation of female genital tuberculosis, accounting for 2.4% of female genital tract tuberculosis cases. Although genitourinary tuberculosis is a common form of extrapulmonary tuberculosis, it most frequently affects the kidneys, bladder, ureters, and fallopian tubes, with cervical involvement being uncommon and often underdiagnosed because of its nonspecific presentation. Three women aged 29, 33, and 40 years from Ethiopia with histologically confirmed cervical tuberculosis who presented with odorless whitish vaginal discharge, pelvic pain, and abnormal uterine bleeding are reported in the present study. All were initially clinically suspected of having cervical cancer because of abnormal cervical findings and abnormal discharge. However, histopathological examination confirmed isolated cervical tuberculosis without systemic involvement. All patients achieved complete clinical resolution after a 6-month course of first-line anti-tuberculosis therapy. These cases highlight the importance of considering cervical tuberculosis in the differential diagnosis of cervical lesions in tuberculosis-endemic settings.
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7. Management of Bullous Pemphigoid and Norwegian Scabies with Dupilumab Plus Ivermectin.
PMID:日期:2026-09-22Bullous pemphigoid is a severe autoimmune blistering disease, and Norwegian scabies is a rare comorbidity. However, conventional treatment methods, such as systemic corticosteroids, carry a high risk in the treatment of elderly patients. Herein, this rare comorbidity is described in an elderly patient. After an initial induction treatment with a low-to-moderate dose of corticosteroid, this patient achieved complete remission with a combination therapy of dupilumab (a monoclonal antibody targeting the interleukin-4/13 signaling pathway) and ivermectin. Therefore, the successful treatment of this rare case provides a promising strategy for reducing reliance on corticosteroids in high-risk populations.
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8. Comparison of Methods for Assessing Chlamydia trachomatis Transmission Intensity: A Systematic Review.
PMID:日期:2026-09-22Field-graded trachomatous inflammation-follicular (TF) has limitations as the sole indicator of Chlamydia trachomatis (Ct) transmission for trachoma programmatic decision-making. To assess the relationship between field-graded TF and other methodologies for evaluating Ct transmission intensity, a systematic review was conducted. A total of 35,764 studies were screened, yielding 235 included studies from 49 countries spanning the years of data collection from 1991 to 2021 and the years of publication from 1991 to 2022. The relationship between TF and other indicators was stronger before mass drug administration (MDA) versus after MDA initiation: TF versus infection (R2 = 0.43, P = 0.004 versus R2 = 0.05, P = 0.140, respectively), TF versus seroprevalence (R2 = 0.55, P <0.001 versus R2 = 0.09, P = 0.084, respectively), and TF versus seroconversion rate (SCR; R2 = 0.52, P = 0.012 versus R2 = 0.26, P = 0.061, respectively). Post-MDA initiation, infection and SCR were highly correlated (R2 = 0.71, P = 0.001). These results are strongly suggestive of the poor performance of TF prevalence for guiding programmatic decision-making post-MDA initiation. Infection and/or serology should be considered in these settings.
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9. Predictors of Changes in Weight and Body Composition in Undernourished Children in Mozambique: A Longitudinal Study.
PMID:日期:2026-09-22Undernutrition is a major public health challenge in Mozambique, requiring a better understanding of changes in weight and body composition. In the present study, changes in weight and body composition were analyzed in undernourished children, and predictors of these changes were identified during and after hospitalization. A longitudinal cohort study was conducted in Maputo, Mozambique (2018-2020), in children aged 6 to 58 months hospitalized for malnutrition. On hospital admission, clinical data, including anemia, edema, and HIV infection status, were collected. Anthropometric measurements, height, weight, and skinfold thickness, were obtained during hospital and community follow-ups. Stool samples were collected to assess intestinal parasitic infections. Longitudinal linear mixed-effects models were used to identify factors associated with changes in weight and proxies of body composition (sum of skinfolds and percentage body fat [%BF]) over time. A total of 217 children were included, with a mean age of 19.2 ± 8.4 months. On admission, 43.7% (94/215) of patients had kwashiorkor, 88.7% (188/212) had anemia, and 55.8% (121/217) had edema. HIV infection was diagnosed in 25.7% (55/214) of patients, and 26.7% (58/217) were positive for intestinal parasitic infections. HIV infection was a strong predictor associated with lower weight gain and body composition change over time (sum of skinfold and estimated %BF), whereas edema was associated with increased gains (P <0.001). Intestinal parasitic infections were associated with weight changes only in univariate analysis (P <0.05). HIV infection and edema at admission were major determinants of recovery, emphasizing targeted HIV care and continued edema monitoring.