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- DREAMSPHEN:一项随机对照研究,比较了基于患者精神病表型分层后精神分裂症谱系障碍患者抗精神病药物剂量减少与维持治疗的差异——个性化医疗方法的研究方案
DREAMSPHEN: a randomised controlled study comparing dose reduction of antipsychotics vs maintenance treatment in schizophrenia spectrum disorder after stratification based on patients' psychotic phenotype - study protocol of a personalised medicine approach.
PMID: 42285570 · 2026 年
- 整合炎症、胰岛素抵抗和内脏脂肪:在一项全国性前瞻性队列研究中,C-反应蛋白甘油三酯葡萄糖中国内脏脂肪指数(CTI-CVAI)与CKM 0-3期的心血管疾病风险相关
Integrating inflammation, insulin resistance, and visceral adiposity: the C-reactive protein-triglyceride-glucose-Chinese visceral adiposity (CTI-CVAI) index is associated with cardiovascular disease risk across CKM stages 0-3 in a nationwide prospective cohort.
PMID: 42286579 · 2026 年
- 牙周炎和类风湿性关节炎的机制证据
Periodontitis and Rheumatoid Arthritis-Mechanistic Evidence.
PMID: 42286863 · 2026 年
- 用于金属增材制造中实时缺陷预测的数字孪生驱动多尺度建模
Digital twin-driven multiscale modelling for real-time defect prediction in metal additive manufacturing.
PMID: 42289574 · 2026 年
- 基于临床数据的围绝经期妇女骨质减少的可解释预测机器学习模型:一项回顾性单中心研究
An explainable predictive machine learning model of osteopenia for perimenopausal women based on clinical data: a retrospective single-center study.
PMID: 42290857 · 2026 年
- 机器学习将PPARG确定为与CD14/NF-κB信号传导相关的败血症诊断生物标志物:综合转录组学和实验验证
Machine learning identifies PPARG as a diagnostic biomarker for sepsis linked to CD14/NF-κB signaling: integrated transcriptomics and experimental validation.
PMID: 42291298 · 2026 年
- NLR炎症小体通路:代谢性疾病发病机制与治疗的关键靶点
NLR inflammasome pathways: key targets for pathogenesis and therapy of metabolic diseases.
PMID: 42292355 · 2026 年
- FABP4在类风湿性关节炎相关性骨质疏松症中的潜在作用:综合生物信息学分析和实验验证
The potential involvement of FABP4 in rheumatoid arthritis-associated osteoporosis: a comprehensive bioinformatics analysis and experimental validation.
PMID: 42292400 · 2026 年
- 病例报告:一名患有SLE和继发性APS的孕妇成功地非手术治疗了巨大的孤立性三尖瓣Libman Sacks心内膜炎
Case Report: successful non-surgical management of massive isolated tricuspid Libman-Sacks endocarditis in a pregnant patient with SLE and secondary APS.
PMID: 42292460 · 2026 年
- 疼痛沟通和外化的结构化和具体化框架(SAEF)
A structured and embodied framework (SAEF) for pain communication and externalization.
PMID: 42292869 · 2026 年
- 肝硬化患者食管和胃静脉曲张的临床试验评估:一个集中式盲法评估系统
Assessment of Esophageal and Gastric Varices in Patients With Cirrhosis for Clinical Trials: A Centralized Blinded Evaluation System.
PMID: 42293772 · 2026 年
- L5/S1前路腰椎椎间融合术:解剖学和技术考量
L5/S1 anterior lumbar interbody fusion: anatomical and technical considerations.
PMID: 42294383 · 2026 年
- 新型a类β-内酰胺酶BAS-1的特性研究
{"_":"Characterization of BAS-1, a novel class A β-lactamase encoded in .","i":["Bacteroides thetaiotaomicron"]}
PMID: 42294649 · 2026 年
- UFM1受体的系统发现揭示了DNA修复中指导非同源末端连接的调控模块
Systematic discovery of UFM1 receptors reveals a regulatory module in DNA repair directing non-homologous end-joining.
PMID: 42297806 · 2026 年
- DNMT1介导的中枢杏仁核至蓝斑回路导致小鼠慢性疼痛相关抑郁
DNMT1-mediated central amygdala to locus coeruleus circuit contributes to chronic pain-related depression in mice.
PMID: 42298205 · 2026 年
- 毒液免疫疗法的衰退:患者特征和临床结果
Declining venom immunotherapy: patient characteristics and clinical outcomes.
PMID: 42298678 · 2026 年
- 放置子宫栓对骨盆解剖的影响:一项使用直立MRI的前瞻性观察研究
The Effect of Pessary Insertion on Pelvic Anatomy: A Prospective Observational Study Using Upright MRI.
PMID: 42298778 · 2026 年
- 山楂原花青素提取物通过重塑肠道微生物群驱动的胆汁酸谱和调节FXR通路,减轻小鼠非酒精性脂肪肝
{"_":"The hawthorn () procyanidin extract attenuates nonalcoholic fatty liver disease in mice remodeling the bile acid profile driven by gut microbiota and regulating the FXR pathway.","i":["Crataegus pinnatifida","via"]}
PMID: 42300918 · 2026 年
- 巨噬细胞膜仿生脂质体靶向递送及ROS响应性释放celastrol缓解急性肾损伤
Targeted delivery and ROS-responsive release of celastrol by a macrophage membrane biomimetic liposome alleviates acute kidney injury.
PMID: 42301266 · 2026 年
- 一种新的非正则Src哺乳动物STE20样激酶1(MST1)-Akt/糖原合酶激酶-3β(GSK3β)通路驱动血小板活化和血栓形成
A novel noncanonical Src-MST1-Akt/GSK3β pathway drives platelet activation and thrombosis.
PMID: 42303155 · 2026 年