【中药治疗肾脏疾病活性成分纳米递送系统的研究进展】
[Research progress in nano-delivery systems of active ingredients in TCM for treating kidney diseases].
摘要(中文译文)
肾脏疾病的发病率不断上升，对全球公共卫生构成了严重挑战。现代医学治疗存在诸多局限性，而中医药治疗肾脏疾病面临生物利用度低和靶向性不足的问题。纳米颗粒独特的物理化学性质使纳米颗粒药物递送系统（NDDS）能够通过被动和主动靶向策略实现对肾脏疾病中药活性成分的精准靶向。本文系统阐述了NDDS的定义、分类、物理化学因素及核心优势。此外，总结了NDDS在多种肾脏疾病中的应用及机制，并讨论了其临床转化面临的挑战和未来前景。本综述旨在为中医药精准治疗肾脏疾病开辟新路径。
Abstract
Kidney diseases, with rising incidences, pose a serious challenge to global public health. Modern medical treatments exhibit numerous limitations, while TCM approaches for kidney diseases face low bioavailability and insufficient targeting. The unique physicochemical properties of nanoparticles enable nanoparticle drug delivery systems(NDDS) to achieve precise targeting of TCM active ingredients for kidney diseases through passive and active targeting strategies. This paper systematically describes the definition, classification, physicochemical factors, and core advantages of NDDS. Furthermore, it summarizes the applications and mechanisms of NDDS in various kidney diseases and discusses the challenges and future prospects for clinical translation. This review aims to establish a novel path for the precision treatment of kidney diseases with TCM.
如何引用
AMA
Zheng Chen, Zhi Chen, Zhi-Qiang Lu, Hong-Yan Tan, Jin-Lian Chen, Shu-Juan Hu, et al. [Research progress in nano-delivery systems of active ingredients in TCM for treating kidney diseases].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2026; doi:10.19540/j.cnki.cjcmm.20260430.303.
APA
Zheng Chen, Zhi Chen, Zhi-Qiang Lu, Hong-Yan Tan, Jin-Lian Chen, Shu-Juan Hu, et al (2026). [Research progress in nano-delivery systems of active ingredients in TCM for treating kidney diseases].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. https://doi.org/10.19540/j.cnki.cjcmm.20260430.303
GB/T 7714
Zheng Chen, Zhi Chen, Zhi-Qiang Lu, Hong-Yan Tan, Jin-Lian Chen, Shu-Juan Hu, et al. [Research progress in nano-delivery systems of active ingredients in TCM for treating kidney diseases].[J]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2026 doi:10.19540/j.cnki.cjcmm.20260430.303.
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