儿科区域麻醉试验中的患者报告结局：当前应用与局限性
Patient-reported outcomes in pediatric regional anesthesia trials: current use and limitations.
摘要(中文译文)
本综述探讨了患者报告结局测量工具（PROMs）在儿童区域麻醉研究中的当前应用与局限性。尽管以患者为中心的结局日益受到重视，现有的儿童结局评估框架可能不足以充分捕捉疼痛体验及其对日常生活的干扰。在已确定的17项随机对照试验和15项正在进行的研究中，PROMs的使用仍高度不一致，普遍依赖于观察性疼痛量表，如面部、腿部、活动、哭泣和可安慰性量表（FLACC），而标准化、纵向健康相关生活质量测量工具的应用则较为有限。当前儿童PROMs框架仍呈碎片化状态，限制了对康复情况的全面评估。需要进一步推进标准化，并纳入与发育阶段相适应的纵向结局测量工具，以更好地使临床研究与有意义的以患者为中心的终点相一致，并改善对功能和社会心理康复的评估。
Abstract
This review examines the current use and limitations of patient-reported outcome measures (PROMs) in pediatric regional anesthesia research. Despite the increasing emphasis on patient-centered outcomes, existing pediatric outcome assessment frameworks may inadequately capture the pain experience and interference with daily living. Across 17 identified randomized controlled trials and 15 ongoing studies, PROM use remains highly variable, with consistent reliance on observational pain scales such as the Face, Legs, Activity, Cry, and Consolability scale and limited incorporation of standardized, longitudinal health-related quality-of-life measures. Current pediatric PROM frameworks remain fragmented, limiting comprehensive evaluation of recovery. Greater standardization and incorporation of developmentally appropriate, longitudinal outcome measures are needed to better align clinical research with meaningful patient-centered endpoints and to improve assessment of functional and psychosocial recovery.
如何引用
AMA
Renee Ren, Helen S Jung, Michelle Carley, Alexandra Sideris, Jashvant Poeran. Patient-reported outcomes in pediatric regional anesthesia trials: current use and limitations.. Current opinion in anaesthesiology. 2026; doi:10.1097/ACO.0000000000001701.
APA
Renee Ren, Helen S Jung, Michelle Carley, Alexandra Sideris, Jashvant Poeran (2026). Patient-reported outcomes in pediatric regional anesthesia trials: current use and limitations.. Current opinion in anaesthesiology. https://doi.org/10.1097/ACO.0000000000001701
GB/T 7714
Renee Ren, Helen S Jung, Michelle Carley, Alexandra Sideris, Jashvant Poeran. Patient-reported outcomes in pediatric regional anesthesia trials: current use and limitations.[J]. Current opinion in anaesthesiology, 2026 doi:10.1097/ACO.0000000000001701.
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