踝间收缩压差与非糖尿病高血压患者的微量白蛋白尿相关:一项来自两个队列的横断面研究
Inter-ankle systolic blood pressure difference is associated with microalbuminuria in non-diabetic hypertension patients: A cross-sectional study from two cohorts.
Inter-ankle systolic blood pressure difference is associated with microalbuminuria in non-diabetic hypertension patients: A cross-sectional study from two cohorts.
这项横断面研究旨在分析踝间收缩压差值(sIAND)是否与高血压肾损害的不同阶段相关。研究从两个队列中纳入了1,658例和831例非糖尿病高血压患者。高血压肾损害通过尿白蛋白与肌酐比值(UACR)、胱抑素C和估算肾小球滤过率来反映。Logistic回归结果显示,sIAND仅独立地与以微量白蛋白尿(UACR > 30 mg/g)反映的亚临床高血压肾损害相关。受试者工作特征曲线表明,sIAND能更有效地识别微量白蛋白尿。sIAND有助于识别微量白蛋白尿,为风险分层和临床管理提供有用的线索。
This cross-sectional study aimed to analyze whether inter-ankle systolic blood pressure difference (sIAND) was associated with different stages of hypertensive renal damage. 1,658 and 831 nondiabetic hypertensive patients were included from two cohorts. The hypertensive renal damage was reflected by urinary albumin-to-creatinine ratio (UACR), Cystatin C, and estimated glomerular filtration rate. Logistic regression results showed that sIAND was only associated with subclinical hypertensive renal damage reflected by microalbuminuria (UACR > 30 mg/g) independently. Receiver operating characteristic curves indicated sIAND can identify microalbuminuria more effectively. sIAND can aid in identifying microalbuminuria to provide useful clues for risk stratification and clinical management.
Yuanyuan Shi, Pengjie Gao, Xingyue Lin, Molei Zhang, Danni Wang, Kamila Kamili, et al. Inter-ankle systolic blood pressure difference is associated with microalbuminuria in non-diabetic hypertension patients: A cross-sectional study from two cohorts.. Clinical and experimental hypertension (New York, N.Y. : 1993). 2026; doi:10.1080/10641963.2026.2712543.
Yuanyuan Shi, Pengjie Gao, Xingyue Lin, Molei Zhang, Danni Wang, Kamila Kamili, et al (2026). Inter-ankle systolic blood pressure difference is associated with microalbuminuria in non-diabetic hypertension patients: A cross-sectional study from two cohorts.. Clinical and experimental hypertension (New York, N.Y. : 1993). https://doi.org/10.1080/10641963.2026.2712543
Yuanyuan Shi, Pengjie Gao, Xingyue Lin, Molei Zhang, Danni Wang, Kamila Kamili, et al. Inter-ankle systolic blood pressure difference is associated with microalbuminuria in non-diabetic hypertension patients: A cross-sectional study from two cohorts.[J]. Clinical and experimental hypertension (New York, N.Y. : 1993), 2026 doi:10.1080/10641963.2026.2712543.
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