在脂肪存在的情况下分析短T2*组织的双组分和三组分方法的比较：应用于跟腱
{"_":"Comparison of bi- and tri-component approaches for the analysis of short-T tissues in the presence of fat: application to the Achilles tendon.","sub":["2"],"sup":["*"]}
摘要(中文译文)
评估数据采集和后处理选择如何影响基于超短回波时间（UTE）的跟腱短T*成分结构表征。十名健康志愿者（33.3 ± 6.9岁）采用多回波、时间交错UTE序列接受跟腱MRI检查。T*数据分别在有无脂肪抑制条件下使用两种模型进行分析：（i）包含两个水池的双成分衰减模型，以及（ii）包含两个水成分和一个脂肪成分的三成分衰减模型。同时评估了幅度拟合与复数拟合对成分估计的影响。分析了三个跟腱区域：止点（INS）、中段（MID）和肌腱-肌肉连接处（MTJ）。估计的短T*与长T*成分因是否使用脂肪抑制（所有肌腱区域p < 0.001）及拟合方法（幅度拟合与复数拟合）（p = 0.002，p < 0.001，p < 0.001）而存在显著差异。T*时间常数相对稳定，尤其在MID区域（p > 0.05）。拟合方法影响MTJ的短T*成分（p = 0.032）以及INS和MTJ的长T*成分（p = 0.025，p < 0.017）。非脂肪抑制与脂肪抑制（FS）策略及拟合方法对跟腱双成分T*定量产生实质性影响，限制了基于UTE的指标的可比性。三成分建模能更真实地描述肌腱信号，并可能提高对病理变化的敏感性。尚需在患者中开展进一步研究。
Abstract
To evaluate how data acquisition and post-processing choices influence ultrashort echo time (UTE)-based characterization of the short-T compositional structure of the Achilles tendon. Ten healthy volunteers (33.3 ± 6.9 years) underwent Achilles tendon MRI using a multi-echo, time-interleaved UTE sequence. T data were analyzed with and without fat suppression using two models: (i) a bi-component decay with two water pools and (ii) a tri-component decay including two water components and one fat component. The effect of magnitude versus complex fitting on compositional estimates was also assessed. Three Achilles tendon regions were analyzed: insertion (INS), mid-portion (MID), and muscle-tendon junction (MTJ). Estimated short vs. long T components differed significantly depending on the use of fat suppression (p < 0.001 for all tendon regions) and fitting method (magnitude vs. complex) (p = 0.002, p < 0.001, p < 0.001). T time constants were comparatively stable, particularly in the MID part (p > 0.05). The fitting method affected short T component in the MTJ (p = 0.032) and long T* component in the INS and MTJ (p = 0.025, p < 0.017). Non-fat-suppressed vs. fat-suppressed (FS) strategy and fitting approach substantially affect bi-component T quantification of the Achilles tendon, limiting comparability of UTE-based metrics. Tri-component modeling provides a more realistic description of tendon signal and may improve sensitivity to pathological changes. Further studies in patients are needed.
如何引用
AMA
Peter Latta, Veronika Janacova, Martin Kojan, Lubomir Vojtíšek, Aneta Malá, Zenon Starčuk, et al. {"_":"Comparison of bi- and tri-component approaches for the analysis of short-T tissues in the presence of fat: application to the Achilles tendon.","sub":["2"],"sup":["*"]}. Magma (New York, N.Y.). 2026; doi:10.1007/s10334-026-01383-2.
APA
Peter Latta, Veronika Janacova, Martin Kojan, Lubomir Vojtíšek, Aneta Malá, Zenon Starčuk, et al (2026). {"_":"Comparison of bi- and tri-component approaches for the analysis of short-T tissues in the presence of fat: application to the Achilles tendon.","sub":["2"],"sup":["*"]}. Magma (New York, N.Y.). https://doi.org/10.1007/s10334-026-01383-2
GB/T 7714
Peter Latta, Veronika Janacova, Martin Kojan, Lubomir Vojtíšek, Aneta Malá, Zenon Starčuk, et al. {"_":"Comparison of bi- and tri-component approaches for the analysis of short-T tissues in the presence of fat: application to the Achilles tendon.","sub":["2"],"sup":["*"]}[J]. Magma (New York, N.Y.), 2026 doi:10.1007/s10334-026-01383-2.
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