微/纳米电机：生物医学应用和挑战
Micro/nanomotors: Biomedical applications and challenges.
摘要(中文译文)
微/纳米马达展现出卓越的应用前景，例如血栓消融、生物膜根除、诊断和生物成像。此外，刺激驱动下微/纳米马达设计的进展实现了可控引导、速度和方向性的提升、体内屏障通透性的增强、货物/药物的靶向性、在 desired 部位的蓄积以及更深的组织穿透。有趣的是，由生物细胞或组分（如精子）构建的生物杂化微/纳米马达展现出优异的生物相容性和潜在的生物医学应用。本综述重点介绍了微/纳米马达的各种构建方法和类型、生物医学应用，以及成功实现临床转化所面临的剩余挑战。
Abstract
Micro/nanomotors show exceptional applications, such as thrombus ablation, biofilm eradication, diagnosis, and bioimaging. In addition, stimulus-driven advances in micro/nanomotor design enable controlled guidance, improved speed and directionality, enhanced in vivo barrier permeability, targetability of cargo/drugs, accumulation at desired sites, and deeper tissue penetration. Interestingly, biohybrid micro/nanomotors constructed with biological cells or components (such as sperm) demonstrate excellent biocompatibility and potential biomedical applications. This review highlights the various approaches to construction and types of micro/nanomotors, biomedical applications, and the remaining challenges for successful clinical translation.
如何引用
AMA
Farhan Mazahir. Micro/nanomotors: Biomedical applications and challenges.. Drug discovery today. 2026; doi:10.1016/j.drudis.2026.104701.
APA
Farhan Mazahir (2026). Micro/nanomotors: Biomedical applications and challenges.. Drug discovery today. https://doi.org/10.1016/j.drudis.2026.104701
GB/T 7714
Farhan Mazahir. Micro/nanomotors: Biomedical applications and challenges.[J]. Drug discovery today, 2026 doi:10.1016/j.drudis.2026.104701.
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