iStent Inject W®颞位与鼻位的比较

摘要(中文译文)

本研究旨在比较在白内障超声乳化手术中，iStent Inject W®植入鼻侧与颞侧对眼压的影响。在连续5年间，回顾性纳入了一家三级转诊中心接受超声乳化联合2枚iStent Inject W®植入的244例患者共389只眼。50.6%的右眼在鼻下方区域植入2枚iStent Inject W®，而49.4%的左眼在颞下方区域接受植入。主要参数为眼压和青光眼用药数量。术后1个月，鼻侧植入的右眼[-1.2（6.7）mmHg]与颞侧植入的左眼[-1.2（6.7）mmHg；P=0.71]之间眼压平均（标准差）变化无显著差异，鼻侧植入的右眼[-0.4（1.3）]与颞侧植入的左眼[-0.5（1.3）；P=0.67]之间青光眼用药数量平均（标准差）变化也无显著差异。在6个月或12个月时同样无显著差异。对双眼均接受手术的患者进行亚组分析，发现1、6或12个月时眼压或青光眼用药变化均无显著差异。并发症发生率较低。iStent Inject W®的疗效不依赖于其植入区域。基于这些结果，我们提出iStent Inject W®可根据术者偏好选择颞侧或鼻侧植入。这对于简化和加快手术流程具有重要意义，并可能改善患者的手术结局。

Abstract

The goal of the present study was to compare the effect of nasal versus temporal placement of the iStent Inject W® during phacoemulsification on intraocular pressure (IOP). Over 5 consecutive years, 389 eyes of 244 patients undergoing phacoemulsification with 2 iStent Inject W® injections in a tertiary referral center were included retrospectively. In 50.6% of eyes, 2 iStent Inject W® were injected in the inferior nasal region of right eyes, while 49.4% received injections in the inferior temporal region of left eyes. The main parameters were IOP and the number glaucoma medications. One month after surgery, there was no significant difference in the mean (SD) change in IOP between right eyes injected nasally [-1.2 (6.7) mmHg] and left eyes injected temporally [-1.2 (6.7) mmHg; P=0.71] and no significant difference in the mean (SD) change in the number of glaucoma medications for the right eyes injected nasally [-0.4 (1.3)] and left eyes injected temporally [-0.5 (1.3); P=0.67]. There was also no significant difference at 6 months or 12 months. Subgroup analysis in patients who underwent surgery in both eyes found no significant difference in IOP or change in glaucoma medications at 1, 6, or 12 months. The complication rate was low. The efficacy of the iStent Inject W® is not dependent on its area of implantation. From these results, we propose that iStent Inject W® can be injected either temporally or nasally based on the surgeon's preferences. This has significant implications for simplifying and speeding up the procedure and might result in improved surgical outcomes for the patient.

如何引用