使用鼻肠梗阻管和肠镜诊断嗜酸性肠炎继发的小肠梗阻:病例报告
Diagnosis of small bowel obstruction secondary to eosinophilic enteritis using nasointestinal ileus tube and enteroscopy: a case report.
Diagnosis of small bowel obstruction secondary to eosinophilic enteritis using nasointestinal ileus tube and enteroscopy: a case report.
背景:以小肠梗阻为主要表现的嗜酸性粒细胞性肠炎诊断困难。本文报道一例局限于回肠上段的嗜酸性粒细胞性肠炎,表现为低位小肠梗阻,经鼻肠梗阻导管联合小肠镜确诊。病例介绍:患者为52岁女性,因间歇性全腹绞痛入院。体格检查发现脐周压痛。腹部CT显示节段性小肠壁增厚、管腔狭窄伴黏膜强化。经无痛球囊小肠镜检查发现局限性回肠炎伴一处狭窄。活检病理显示固有层大量嗜酸性粒细胞浸润,确诊为嗜酸性粒细胞性肠炎。患者经糖皮质激素治疗后症状明显改善,12个月随访期间未见复发。结论:本病例提示,对于小肠梗阻患者,即使外周血嗜酸性粒细胞计数正常,也应考虑嗜酸性粒细胞性肠炎的可能。小肠镜活检是诊断嗜酸性粒细胞性肠炎的关键方法,而鼻肠梗阻导管可解除肠梗阻,为小肠镜检查创造有利条件。
BACKGROUND: Eosinophilic enteritis presenting primarily with small bowel obstruction is challenging to diagnose. This article reports a case of eosinophilic enteritis localized in the upper ileum, manifesting as low small bowel obstruction, which was confirmed by nasointestinal ileus tube combined with enteroscopy. CASE PRESENTATION: A 52-year-old female was admitted due to intermittent generalized abdominal colic. Physical examination revealed periumbilical tenderness. Abdominal CT showed segmental small bowel wall thickening, luminal stenosis with mucosal enhancement. Painless balloon enteroscopy detected localized ileitis with one stenosis. Biopsy pathology showed massive eosinophilic infiltration in the lamina propria, confirming the diagnosis of eosinophilic enteritis. The patient's symptoms improved significantly after glucocorticoid treatment, and no recurrence was observed during the 12-month follow-up period. CONCLUSIONS: This case suggests that for patients with small bowel obstruction, eosinophilic enteritis should be considered even if the peripheral blood eosinophil count is normal. Enteroscopic biopsy is the key method for diagnosing eosinophilic enteritis, and nasointestinal ileus tube can relieve intestinal obstruction to create favorable conditions for enteroscopy.
Ya-Nan Wang, Yan Shao, Chun-di Guan, Qian Li, Wei Wang. Diagnosis of small bowel obstruction secondary to eosinophilic enteritis using nasointestinal ileus tube and enteroscopy: a case report.. BMC gastroenterology. 2026; doi:10.1186/s12876-026-04819-0.
Ya-Nan Wang, Yan Shao, Chun-di Guan, Qian Li, Wei Wang (2026). Diagnosis of small bowel obstruction secondary to eosinophilic enteritis using nasointestinal ileus tube and enteroscopy: a case report.. BMC gastroenterology. https://doi.org/10.1186/s12876-026-04819-0
Ya-Nan Wang, Yan Shao, Chun-di Guan, Qian Li, Wei Wang. Diagnosis of small bowel obstruction secondary to eosinophilic enteritis using nasointestinal ileus tube and enteroscopy: a case report.[J]. BMC gastroenterology, 2026 doi:10.1186/s12876-026-04819-0.
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