印度专家对女性变应性鼻炎的共识：改良德尔菲调查

摘要(中文译文)

目前，在理解印度女性过敏性鼻炎患者的临床需求方面仍存在许多显著空白。为弥补临床实践中的关键缺口，共识小组制定了一份创新性问卷，专门用于协助印度临床医生对女性患者过敏性鼻炎进行诊断和管理。改良德尔菲调查采用系统化的群体沟通方法，通过详细评估各种论据来解决研究问题并化解观点分歧。共制定了80条陈述，聚焦于过敏性鼻炎的疾病负担、危险因素、临床表现、合并症、症状及治疗。在专家小组审查的61条陈述中，约38条获得了超过80%的同意率，从而达成共识。过敏性疾病在印度女性中更为常见，对其影响尤为严重。高度共识表明，许多印度女性大部分时间待在室内，这可能导致其更多地接触室内过敏原和污染物，进而增加其对过敏的易感性。专家们还就评估和管理印度女性过敏性鼻炎患者可改变和不可改变的过敏原提供了真实世界的临床建议。

Abstract

At present, there are many significant gaps in understanding the clinical needs of Indian women with allergic rhinitis. To address a critical gap in clinical practice, the consensus group created an innovative questionnaire tailored to assist Indian clinicians in the diagnosis and management of allergic rhinitis among female patients. The modified Delphi survey utilized a systematic approach to group communication in addressing research questions and resolving conflicting viewpoints through detailed evaluation of various arguments. In total, 80 statements were developed focusing on disease burden, risk factors, clinical presentation, comorbidities, symptoms, and treatment of allergic rhinitis. Out of 61 statements reviewed by the expert panel, around 38 statements received over 80% agreement, leading to a consensus. Allergic conditions are more common among Indian women, impacting them disproportionately. A high level of consensus indicates that many Indian women spend most of their time indoors, which can result in heightened exposure to indoor allergens and pollutants, consequently increasing their vulnerability to allergies. The experts also offered real-world clinical recommendations while assessing and managing modifiable and nonmodifiable allergens in Indian women with allergic rhinitis.

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