急诊科和重症监护室入院的脓毒症患者qSOFA评分和NEWS2评分作为患者预后指标的比较
Comparison of qSOFA Score and NEWS2 Score in Sepsis Patients Admitted in Emergency Department and ICU as Prognostic Markers of Patient Outcome.
摘要(中文译文)
脓毒症在急诊和重症监护环境中导致较高的短期死亡率。快速序贯器官衰竭评估（qSOFA）和国家早期预警评分2（NEWS2）是用于早期风险分层的床旁工具，但两者的比较证据仍然有限。旨在比较qSOFA和NEWS2对成人脓毒症患者7天和28天死亡率及住院时间的预测价值。这项前瞻性观察性研究在印度北部一家三级医疗中心进行，为期1年（2024年3月至2025年2月）。共纳入874例因脓毒症入院的18至65岁患者。记录入院时的qSOFA和NEWS2评分。结局包括7天死亡率、28天死亡率和住院时间。在874例患者中，NEWS2对7天死亡率（63.1% vs 35.1%）和28天死亡率（64.1% vs 37.3%）的敏感性高于qSOFA，特异性相当（约86%）。受试者工作特征曲线下面积（AUROC）值在7天死亡率（0.627 vs 0.606）和28天死亡率（0.629 vs 0.609）方面均支持NEWS2。在成人脓毒症患者中，NEWS2评分在预测短期死亡率和住院时间方面显示出比qSOFA更高的敏感性和略优的预后准确性。因此，NEWS2可作为急诊和重症监护环境中早期识别高危患者的更可靠床旁工具。
Abstract
Sepsis causes high short-term mortality in emergency and ICU settings. Quick sequential organ failure assessment (qSOFA) and national early warning score 2 (NEWS2) are bedside tools for early risk stratification, yet comparative evidence remains limited. To compare qSOFA and NEWS2 for predicting 7-day and 28-day mortality and length of stay in adult sepsis patients. This prospective observational study was conducted over 1 year (March 2024-February 2025) at a tertiary care center in northern India. A total of 874 patients aged 18-65 years admitted with sepsis were enrolled. On-admission qSOFA and NEWS2 scores were recorded. Outcomes included 7-day, 28-day mortality and length of hospital stay. Among 874 patients, NEWS2 showed higher sensitivity than qSOFA for 7-day (63.1% vs 35.1%) and 28-day mortality (64.1% vs 37.3%), with comparable specificity (~86%). Area under receiver operating characteristic curve (AUROC) values favored NEWS2 for 7-day (0.627 vs 0.606) and 28-day mortality (0.629 vs 0.609). In adults with sepsis, the NEWS2 score showed higher sensitivity and marginally better prognostic accuracy than qSOFA for predicting short-term mortality and hospital stay. NEWS2 may therefore serve as a more reliable bedside tool for early identification of high-risk patients in emergency and ICU settings.
如何引用
AMA
Kumar Anupam, Kamal Kumar Sawlani, Ambuj Yadav, Shyam Chand Chaudhary, Kauser Usman, Arzoo Sharma, et al. Comparison of qSOFA Score and NEWS2 Score in Sepsis Patients Admitted in Emergency Department and ICU as Prognostic Markers of Patient Outcome.. The Journal of the Association of Physicians of India. 2026; doi:10.59556/japi.74.1319.
APA
Kumar Anupam, Kamal Kumar Sawlani, Ambuj Yadav, Shyam Chand Chaudhary, Kauser Usman, Arzoo Sharma, et al (2026). Comparison of qSOFA Score and NEWS2 Score in Sepsis Patients Admitted in Emergency Department and ICU as Prognostic Markers of Patient Outcome.. The Journal of the Association of Physicians of India. https://doi.org/10.59556/japi.74.1319
GB/T 7714
Kumar Anupam, Kamal Kumar Sawlani, Ambuj Yadav, Shyam Chand Chaudhary, Kauser Usman, Arzoo Sharma, et al. Comparison of qSOFA Score and NEWS2 Score in Sepsis Patients Admitted in Emergency Department and ICU as Prognostic Markers of Patient Outcome.[J]. The Journal of the Association of Physicians of India, 2026 doi:10.59556/japi.74.1319.
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