Comparing myopia control efficacy and corneal power changes in children wearing corneal refractive therapy (CRT) and vision shaping treatment (VST) orthokeratology lenses with smaller back optic zone diameters.
比较配戴后光学区直径（BOZD）较小的角膜屈光治疗（CRT）镜片与视觉塑形治疗（VST）镜片的儿童眼轴（AL）增长及相对角膜屈光力（RCRP）变化。本回顾性研究纳入136只眼，来自8~11岁、近视度数为-0.50~-3.00 D的儿童，分别配戴两种角膜塑形镜（OK镜）：5.0 mm-BOZD CRT和5.6 mm-BOZD VST。分析检测了基线、6个月和12个月时的AL。通过分析基线和1年后获得的角膜地形图，获取治疗区大小（TZS）、治疗区偏中心（TZD）及RCRP参数。5.6 mm-BOZD VST组的AL增长显著慢于5.0 mm-BOZD CRT组（6个月：0.09 ± 0.08 mm vs. 0.15 ± 0.10 mm；12个月：0.16 ± 0.14 mm vs. 0.31 ± 0.18 mm；均P < 0.001）。与5.0 mm-BOZD CRT组相比，5.6 mm-BOZD VST组显示出更小的3/4X值（表示RCRP曲线首次达到其四分之三峰值处的距离），以及瞳孔区域内更高的RCRP总和值（均P < 0.05）。然而，两组的最大RCRP值、TZS和TZD相似。在8~11岁低度近视儿童中，5.6 mm-BOZD VST镜片比5.0 mm-BOZD CRT镜片提供了更优的近视控制效果，主要通过诱导更陡峭的RCRP曲线及瞳孔区域内更大的RCRP总和值实现。
To compare axial length (AL) elongation and relative corneal refractive power (RCRP) changes in children wearing corneal refractive therapy (CRT) and vision shaping treatment (VST) lenses with smaller back optical zone diameters (BOZD). This retrospective study included136 eyes from children aged 8-11 years, having myopia of -0.50 to -3.00 D, which were fitted with two types of orthokeratology (OK) lenses: 5.0 mm-BOZD CRT and 5.6 mm-BOZD VST. The analysis detected AL at baseline, 6 months, and 12 months. The treatment zone size (TZS), treatment zone decentration (TZD) and RCRP parameters were obtained through analyzing the corneal topography maps obtained at baseline and after 1 year. The AL increase in the 5.6 mm-BOZD VST group was significantly slower than the 5.0 mm-BOZD CRT group (6 months: 0.09 ± 0.08 mm vs. 0.15 ± 0.10 mm; 12 months: 0.16 ± 0.14 mm vs. 0.31 ± 0.18 mm; both P < 0.001). The 5.6 mm-BOZD VST group showed a smaller 3/4X value (indicating the distance from which the RCRP profile first reaches its three-quarter peak) and a higher summed RCRP value within the pupillary region compared to the 5.0 mm-BOZD CRT group (both P < 0.05). However, the maximum RCRP value, TZS, and TZD were similar between the two groups. 5.6 mm-BOZD VST lenses provided superior myopia control efficacy compared to 5.0 mm-BOZD CRT lenses in 8-11-year-old children with low myopia, mainly through inducing a steeper RCRP profile and a greater RCRP sum value within the pupillary area.
Na Li, Wenting Jiang, Na Wang, Zhaoying Cai, Bei Du, Weiping Lin, et al. Comparing myopia control efficacy and corneal power changes in children wearing corneal refractive therapy (CRT) and vision shaping treatment (VST) orthokeratology lenses with smaller back optic zone diameters.. Photodiagnosis and photodynamic therapy. 2026; doi:10.1016/j.pdpdt.2026.105482.
Na Li, Wenting Jiang, Na Wang, Zhaoying Cai, Bei Du, Weiping Lin, et al (2026). Comparing myopia control efficacy and corneal power changes in children wearing corneal refractive therapy (CRT) and vision shaping treatment (VST) orthokeratology lenses with smaller back optic zone diameters.. Photodiagnosis and photodynamic therapy. https://doi.org/10.1016/j.pdpdt.2026.105482
Na Li, Wenting Jiang, Na Wang, Zhaoying Cai, Bei Du, Weiping Lin, et al. Comparing myopia control efficacy and corneal power changes in children wearing corneal refractive therapy (CRT) and vision shaping treatment (VST) orthokeratology lenses with smaller back optic zone diameters.[J]. Photodiagnosis and photodynamic therapy, 2026 doi:10.1016/j.pdpdt.2026.105482.
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