HADS-D、PHQ-9和PHQ-2在检测多囊卵巢综合征女性抑郁中的比较
Comparison of HADS-D, PHQ-9 and PHQ-2 for detecting depression in women with polycystic ovary syndrome.
Comparison of HADS-D, PHQ-9 and PHQ-2 for detecting depression in women with polycystic ovary syndrome.
比较使用聚焦抑郁的医院焦虑抑郁量表(HADS-D)、患者健康问卷-9(PHQ-9)和患者健康问卷-2(PHQ-2)所得到的抑郁患病率。同时评估这些工具的心理测量学特性及其在不同临界值下的一致性。一项纳入119名多囊卵巢综合征(PCOS)女性的横断面研究。参与者完成全部三种测量工具以评估抑郁。该研究比较了抑郁患病率,并使用Cohen's Kappa(κ)、一致性系数(ρ)、Spearman相关和Cronbach's alpha(α)分析心理测量学特性。PCOS女性中的抑郁率因筛查工具不同而差异显著:2.52%-26.89%。然而,HADS-D与PHQ-9之间的一致性和相关性较差。相比之下,使用HADS-D ≥ 7和PHQ-9 ≥ 10的临界值时,显示出强一致性(κ = 0.731)和相关性(ρ = 0.731)。PHQ-2 ≥ 3与HADS-D ≥ 7(ρ = 0.596,κ = 0.599)及PHQ-9 ≥ 10(ρ = 0.596,κ = 0.599)具有合理的相关性。PCOS女性的抑郁率因评估方法而异。本研究建议HADS-D采用≥7、PHQ-9采用≥10的临界值,以提高泰国PCOS女性的筛查准确性。PHQ-2因其简短和易用性,也是一种便捷的替代工具。我们提出,PHQ-9评分≥10是泰国PCOS女性最合适的筛查工具。
To compare depression prevalence using the Hospital Anxiety and Depression Scale focused on depression (HADS-D), the Patient Health Questionnaire-9 (PHQ-9) and the Patient Health Questionnaire-2 (PHQ-2). It also evaluated the psychometric properties of these instruments and their agreement at different cutoff scores. A cross-sectional study with 119 women with PCOS. Participants completed all three measurements to assess depression. The study compared depression prevalence and analysed psychometric properties using Cohen's Kappa (), coefficient (), Spearman's correlation and Cronbach's alpha (). Depression rate among PCOS women varied significantly by screening tool: 2.52%-26.89%. However, there was poor agreement and correlation between HADS-D and PHQ-9. In contrast, using cutoff scores of HADS-D ≥ 7 and PHQ-9 ≥ 10 yielded strong agreement ( = 0.731) and correlation ( = 0.731). The PHQ-2 ≥ 3 had reasonable correlations with HADS-D ≥ 7 ( = 0.596, = 0.599) and PHQ-9 ≥ 10 ( = 0.596, = 0.599). Depression rates in PCOS women vary by evaluation technique. This study recommends a cutoff score of ≥7 for the HADS-D and ≥10 for the PHQ-9 to enhance screening accuracy among Thai PCOS women. The PHQ-2 also represents a convenient alternative tool due to its brevity and user-friendliness. We propose that the PHQ-9, with a score of ≥10, constitutes the most suitable screening instrument for Thai women with PCOS.
Siriluk Tantanavipas, Ratana Saipanish, Areepan Sophonsritsuk, Pornsri Niransuk. Comparison of HADS-D, PHQ-9 and PHQ-2 for detecting depression in women with polycystic ovary syndrome.. Journal of psychosomatic obstetrics and gynaecology. 2026; doi:10.1080/0167482X.2026.2660700.
Siriluk Tantanavipas, Ratana Saipanish, Areepan Sophonsritsuk, Pornsri Niransuk (2026). Comparison of HADS-D, PHQ-9 and PHQ-2 for detecting depression in women with polycystic ovary syndrome.. Journal of psychosomatic obstetrics and gynaecology. https://doi.org/10.1080/0167482X.2026.2660700
Siriluk Tantanavipas, Ratana Saipanish, Areepan Sophonsritsuk, Pornsri Niransuk. Comparison of HADS-D, PHQ-9 and PHQ-2 for detecting depression in women with polycystic ovary syndrome.[J]. Journal of psychosomatic obstetrics and gynaecology, 2026 doi:10.1080/0167482X.2026.2660700.
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