低温一锅法制备用于生物监测的双离子导电水凝胶
Low-Temperature One-Pot Fabrication of a Dual-Ion Conductive Hydrogel for Biological Monitoring.
摘要(中文译文)
柔性导电水凝胶在可穿戴电子和生物监测应用中具有广阔前景，但其实际应用受到低温耐受性差、易脱水以及多功能传感能力有限等问题的制约。本研究通过简化的低温一锅聚合法，成功合成了一种基于丙烯酰胺/明胶的双导电锂离子和钙离子水凝胶。在60 °C下，将丙烯酰胺、明胶、氯化锂和氯化钙在40 min内混合，构建了具有共价键、离子键和氢键的网络结构。所得材料表现出优异的延展性，断裂伸长率达1408.5%，拉伸强度为134.2 kPa，同时对九种不同基底保持强粘附力。该水凝胶在-20 °C下仍保持柔性，并在老化10天后表现出极小的质量损失（仅为初始值的3%）。作为传感器，该水凝胶能够可靠地响应压力、温度、大幅度肢体运动以及脉搏和声带振动等细微生理信号。在动物模拟监测中，其电阻信号随模型体重呈线性增加，并在-20 °C至20 °C范围内保持稳定。这些结果表明，该水凝胶在可穿戴传感、生态监测和智慧农业中具有广阔的应用潜力。
Abstract
Flexible conductive hydrogels hold great promise in wearable electronics and biomonitoring applications, yet their practical use is constrained by issues such as poor low-temperature tolerance, susceptibility to dehydration, and limited multifunctional sensing capabilities. This study successfully synthesized a dual-conductive lithium-ion and calcium-ion hydrogel based on acrylamide/gelatin via a simplified low-temperature one-pot polymerization method. At 60 °C, mixing acrylamide, gelatin, lithium chloride, and calcium chloride within 40 min constructed a network structure featuring covalent bonds, ionic bonds, and hydrogen bonds. The resulting material exhibited exceptional extensibility with a break elongation of 1408.5% and tensile strength of 134.2 kPa while maintaining strong adhesion to nine different substrates. It retained flexibility at -20 °C and demonstrated minimal mass loss (3% of initial value) after 10 days of aging. As a sensor, this hydrogel reliably responds to pressure, temperature, large-amplitude body movements, and subtle physiological signals like pulse and vocal cord vibrations. In animal simulation monitoring, its electrical resistance signals increased linearly with model body weight and remained stable between -20 °C and 20 °C. These results demonstrate the hydrogel's broad application potential in wearable sensing, ecological monitoring, and smart agriculture.
如何引用
AMA
Xinyu Guan, Xudong Ma, Ruixi Gao, Qiuju Zheng, Changlong Sun, Yahui Chen, et al. Low-Temperature One-Pot Fabrication of a Dual-Ion Conductive Hydrogel for Biological Monitoring.. Sensors (Basel, Switzerland). 2026; doi:10.3390/s26072086.
APA
Xinyu Guan, Xudong Ma, Ruixi Gao, Qiuju Zheng, Changlong Sun, Yahui Chen, et al (2026). Low-Temperature One-Pot Fabrication of a Dual-Ion Conductive Hydrogel for Biological Monitoring.. Sensors (Basel, Switzerland). https://doi.org/10.3390/s26072086
GB/T 7714
Xinyu Guan, Xudong Ma, Ruixi Gao, Qiuju Zheng, Changlong Sun, Yahui Chen, et al. Low-Temperature One-Pot Fabrication of a Dual-Ion Conductive Hydrogel for Biological Monitoring.[J]. Sensors (Basel, Switzerland), 2026 doi:10.3390/s26072086.
在 PubMed增强版 阅读全文
翻译全文 · AI 文献问答 · PDF 原文下载 · 引用导出