代谢功能障碍相关脂肪变性肝病和心血管风险：一项综合综述
Metabolic dysfunction-associated steatotic liver disease and cardiovascular risk: a comprehensive review.
摘要(中文译文)
代谢功能障碍相关脂肪性肝病（MASLD），既往称为非酒精性脂肪性肝病（NAFLD），因其患病率不断上升且与心血管疾病（CVD）密切相关，构成了重大的全球健康挑战。本综述总结了目前关于MASLD与CVD关系的认识，比较分析了脂肪性肝病不同术语如何影响使用不同诊断标准进行心血管（CV）风险评估，探讨了连接MASLD与CVD的病理生理机制、MASLD对传统CV危险因素的影响、无创影像技术和生物标志物在评估MASLD患者CV风险中的作用，以及对临床管理和预防策略的意义。通过整合当前研究和临床指南，本综述全面概述了MASLD与心血管健康之间复杂的相互作用。
Abstract
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed nonalcoholic fatty liver disease (NAFLD), poses a significant global health challenge due to its increasing prevalence and strong association with cardiovascular disease (CVD). This comprehensive review summarizes the current knowledge on the MASLD-CVD relationship, compares analysis of how different terminologies for fatty liver disease affect cardiovascular (CV) risk assessment using different diagnostic criteria, explores the pathophysiological mechanisms connecting MASLD to CVD, the influence of MASLD on traditional CV risk factors, the role of noninvasive imaging techniques and biomarkers in the assessment of CV risk in patients with MASLD, and the implications for clinical management and prevention strategies. By incorporating current research and clinical guidelines, this review provides a comprehensive overview of the complex interplay between MASLD and cardiovascular health.
如何引用
AMA
Haixiang Zheng, Leonardo Antonio Sechi, Eliano Pio Navarese, Gavino Casu, Gianpaolo Vidili. Metabolic dysfunction-associated steatotic liver disease and cardiovascular risk: a comprehensive review.. Cardiovascular diabetology. 2024; doi:10.1186/s12933-024-02434-5.
APA
Haixiang Zheng, Leonardo Antonio Sechi, Eliano Pio Navarese, Gavino Casu, Gianpaolo Vidili (2024). Metabolic dysfunction-associated steatotic liver disease and cardiovascular risk: a comprehensive review.. Cardiovascular diabetology. https://doi.org/10.1186/s12933-024-02434-5
GB/T 7714
Haixiang Zheng, Leonardo Antonio Sechi, Eliano Pio Navarese, Gavino Casu, Gianpaolo Vidili. Metabolic dysfunction-associated steatotic liver disease and cardiovascular risk: a comprehensive review.[J]. Cardiovascular diabetology, 2024 doi:10.1186/s12933-024-02434-5.
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