类花生酸与肝细胞癌发病机制关联的生物分析见解
Bioanalytical insights into the association between eicosanoids and pathogenesis of hepatocellular carcinoma.
Bioanalytical insights into the association between eicosanoids and pathogenesis of hepatocellular carcinoma.
已有研究指出,炎症与肝细胞癌(HCC)的发生和进展密切相关。源自花生四烯酸的类花生酸在慢性炎症中发挥关键作用。因此,类花生酸与HCC之间存在复杂的关系,这一观点得到了流行病学、临床和基础科学研究的支持。本文旨在从细胞增殖、血管生成、迁移到凋亡等方面,提供类花生酸在HCC进展中作用的生物分析学见解。同时,也对类花生酸的分析方法和生物化学进行了描述。
It has been noted that inflammatory were intimately associated with the development and progression of hepatocellular carcinoma (HCC). Eicosanoids derived from arachidonic acid play crucial roles in chronic inflammation. Accordingly, there is an intricate relationship between eicosanoids and HCC, being supported by the epidemiological, clinical, and basic science studies. Herein, we intend to provide bioanalytical insights into the role of eicosanoids in HCC progression, from cell proliferation, angiogenesis migration, to apoptosis. Also, the analytical methods and biochemistry of eicosanoids are described.
Yong-Jiang Xu, Zhaojun Zheng, Chen Cao, Jinwei Li, Yuanfa Liu. Bioanalytical insights into the association between eicosanoids and pathogenesis of hepatocellular carcinoma.. Cancer metastasis reviews. 2018; doi:10.1007/s10555-018-9747-8.
Yong-Jiang Xu, Zhaojun Zheng, Chen Cao, Jinwei Li, Yuanfa Liu (2018). Bioanalytical insights into the association between eicosanoids and pathogenesis of hepatocellular carcinoma.. Cancer metastasis reviews. https://doi.org/10.1007/s10555-018-9747-8
Yong-Jiang Xu, Zhaojun Zheng, Chen Cao, Jinwei Li, Yuanfa Liu. Bioanalytical insights into the association between eicosanoids and pathogenesis of hepatocellular carcinoma.[J]. Cancer metastasis reviews, 2018 doi:10.1007/s10555-018-9747-8.
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