阿里哌唑治疗人格解体障碍共病重度抑郁和强迫症：3例病例

摘要(中文译文)

人格解体是抑郁症和强迫症（OCD）中常见的症状，但有时它可能较为严重，并同时被诊断为一种障碍。人格解体障碍单独存在或与其他精神障碍共病时的治疗迄今尚不明确。本报告介绍了3例抑郁症或强迫症患者共病人格解体障碍后，经阿立哌唑治疗成功的案例。这些精神障碍均通过结构化临床访谈进行诊断。评估工具包括耶鲁-布朗强迫量表、临床总体印象-改善量表和17项汉密尔顿抑郁评定量表。阿立哌唑可能是治疗共病强迫症或抑郁症的人格解体障碍的一种有益的精神药物，而后者是临床实践中的一个重要问题。

Abstract

Depersonalization is a frequent symptom in depression and obsessive-compulsive disorder (OCD), but sometimes, it may be severe and concurrently diagnosed as a disorder. The treatment of depersonalization disorder both alone and comorbid with other psychiatric disorders is as yet unclear. This report presents the successful treatment with aripiprazole of concurrent depersonalization disorder in 3 patients with depression or OCD. The psychiatric disorders were diagnosed through structured clinical interviews. Assessments were by means of Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression-Improvement Scale, and the 17-item Hamilton Rating Scale for Depression. Aripiprazole may be a beneficial psychotropic drug in the treatment of depersonalization disorder comorbid with OCD or depression, which is an important problem in clinical practice.

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